[HTML][HTML] Parkia javanica Edible Pods Reveal Potential as an Anti-Diabetic Agent: UHPLC-QTOF-MS/MS-Based Chemical Profiling, In Silico, In Vitro, In Vivo, and …

A Sarkar, A Chakrabarti, S Bhaumik, B Debnath… - Pharmaceuticals, 2024 - mdpi.com
According to the World Health Organization, over 422 million people worldwide have
diabetes, with the majority residing in low-and middle-income countries. Diabetes causes …

[HTML][HTML] Therapeutic potential of Hyoscyamus niger-derived compounds: Targeting ovarian cancer through antioxidant activity and EGFR tyrosine kinase inhibition

S Lekmine, O Benslama, K Kadi… - Journal of King Saud …, 2024 - Elsevier
Ovarian cancer poses a significant challenge to women's health, necessitating innovative
therapeutic approaches. This study investigates the therapeutic potential of compounds …

In Silico Design, Synthesis, and Evaluation of Novel Enantiopure Isoxazolidines as Promising Dual Inhibitors of α-Amylase and α-Glucosidase

F Alhawday, F Alminderej, S Ghannay, B Hammami… - Molecules, 2024 - mdpi.com
Isoxazolidine derivatives were designed, synthesized, and characterized using different
spectroscopic techniques and elemental analysis and then evaluated for their ability to …

[HTML][HTML] Elucidating Chiral Resolution of Aromatic Amino Acids Using Glycopeptide Selectors: A Combined Molecular Docking and Chromatographic Study

D Gherdaoui, MM Yahoum, S Toumi… - International Journal of …, 2024 - mdpi.com
An asymmetric synthesis is a favorable approach for obtaining enantiomerically pure
substances, but racemic resolution remains an efficient strategy. This study aims to elucidate …

Molecular Docking Simulation of Phenolics towards Tyrosinase, Phenolic Content, and Radical Scavenging Activity of Some Zingiberaceae Plant Extracts

Mutakin, NM Saptarini, R Amalia, SA Sumiwi… - Cosmetics, 2023 - mdpi.com
In Indonesia, plants have been indigenously used to treat various diseases and as
cosmetics. It is always challenging to explore the molecular interactions of phenolic …

Anti-Cholinergic Effects of the Phenolic Extract from the Astragalus crenatus Plant: A Computational and Network Pharmacology Study

S Lekmine, O Benslama, H Tahraoui, MS Ola… - Pharmaceuticals, 2024 - mdpi.com
Investigations into cholinesterase inhibition have received attention from researchers in
recent years for the treatment of Alzheimer's disease. Cholinesterase enzymes, namely …

Arisarum vulgare: Bridging Tradition and Science Through Phytochemical Characterization and Exploring Therapeutic Potential via In vitro, In vivo, and In silico …

Z Bouafia, A Boudjelal, S Bouaziz‐Terrachet… - …, 2024 - Wiley Online Library
Abstract Arisarum vulgare O. Targ. Tozz.(Araceae), locally known as “Elbgouga,” holds
significant traditional importance in Algeria for the treatment of various human ailments …