Genetic models of human and mouse dendritic cell development and function
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …
numerous shared characteristics between mice and humans. Human counterparts of mouse …
Dendritic cell migration in health and disease
T Worbs, SI Hammerschmidt, R Förster - Nature Reviews Immunology, 2017 - nature.com
Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …
A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation
The mutualistic relationship of gut-resident microbiota and the host immune system
promotes homeostasis that ensures maintenance of the microbial community and of a …
promotes homeostasis that ensures maintenance of the microbial community and of a …
Local IL-23 is required for proliferation and retention of skin-resident memory TH17 cells
The cytokine interleukin-23 (IL-23) is critical for development and maintenance of
autoimmune inflammation in nonlymphoid tissues; however, the mechanism through which …
autoimmune inflammation in nonlymphoid tissues; however, the mechanism through which …
Dendritic cell subsets and locations
S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
Functions of murine dendritic cells
V Durai, KM Murphy - Immunity, 2016 - cell.com
Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …
adaptive immune responses. The functions of DCs were originally obscured by their overlap …
[HTML][HTML] Dysbiosis and Staphylococcus aureus colonization drives inflammation in atopic dermatitis
T Kobayashi, M Glatz, K Horiuchi, H Kawasaki… - Immunity, 2015 - cell.com
Staphylococcus aureus skin colonization is universal in atopic dermatitis and common in
cancer patients treated with epidermal growth factor receptor inhibitors. However, the causal …
cancer patients treated with epidermal growth factor receptor inhibitors. However, the causal …
[HTML][HTML] Cutaneous TRPV1+ neurons trigger protective innate type 17 anticipatory immunity
JA Cohen, TN Edwards, AW Liu, T Hirai, MR Jones… - Cell, 2019 - cell.com
Cutaneous TRPV1+ neurons directly sense noxious stimuli, inflammatory cytokines, and
pathogen-associated molecules and are required for innate immunity against some skin …
pathogen-associated molecules and are required for innate immunity against some skin …
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …
responses according to peripheral cues. After four decades of research, we now know that …
Nociceptive sensory fibers drive interleukin-23 production from CD301b+ dermal dendritic cells and drive protective cutaneous immunity
Innate resistance to Candida albicans in mucosal tissues requires the production of
interleukin-17A (IL-17A) by tissue-resident cells early during infection, but the mechanism of …
interleukin-17A (IL-17A) by tissue-resident cells early during infection, but the mechanism of …