The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

Transition-metal-catalyzed nucleophilic addition of organometallic reagents to polar
unsaturated substrates is one of the most important and powerful bond-forming strategies …

Alkylation of arenes is one of the most fundamental transformations in chemical synthesis
and leads to privileged scaffolds in many areas of science. Classical methods for the …

A 1, 4-addition with the nucleophilic center generated at the ortho carbon atom of an
aromatic ketone in the presence of the highly reactive α-C–H bond, using a directing group …

Saturated azacycles are commonly encountered in bioactive compounds and approved
therapeutic agents. The development of methods for functionalization of the α-methylene C …

A versatile and site-selective rhodium (III)-catalyzed aerobic oxidative alkenylation of
arylacetamides including primary, secondary, and tertiary amides having a weak O …

N-Substituted aromatic and heteroaromatic amides reacted with substituted allylic alcohols
in the presence of a ruthenium catalyst, AgSbF6 and a Cu (OAc) 2· H2O oxidant, affording 3 …

The alkylation of C–H bonds with α, β-unsaturated carbonyl compounds by a rhodium-
catalyzed reaction of aromatic amides containing an 8-aminoquinoline moiety is reported …

Organic syntheses based on the activation of C–H bonds catalysed by transition metals (TM)
are of great interest because new pathways can be designed that were not previously …

A highly selective and switchable ruthenium-catalyzed ortho C–H alkylation and C–H
alkenylation of benzoic acids with allyl alcohols is reported. A complete switch in selectivity …