While a number of genetic mutations are associated with Parkinson's disease (PD), it is also
widely acknowledged that the environment plays a significant role in the etiology of …

Neural stem cells (NSCs), an invaluable source of neuronal and glial progeny, have been
widely interrogated in the last twenty years, mainly to understand their therapeutic potential …

Parkinson's disease (PD) is a progressive neurodegenerative disorder. Various symptoms
and diagnostic tests are used in combination for the diagnosis of PD; however, accurate …

Background Parkinson's disease (PD) is a neurodegenerative disease, and its pathogenesis
is unclear. Previous studies mainly focus on the lesions of substantia nigra (SN) and striatum …

Inherited and acquired defects in neurogenesis contribute to neurodevelopmental disorders,
dysfunctional neural plasticity, and may underlie pathology in a range of neurodegenerative …

Neuronal apoptosis and survival are regulated at the transcriptional level. To identify key
genes and upstream regulators primarily responsible for these processes, we overlayed the …

As a neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP)-preferring
receptor, PAC1-R mediates effective neuroprotective activity. Based on the finding that the …

Transcriptional regulation is fundamental to most biological processes and reverse-
engineering programs can be used to decipher the underlying programs. In this review, we …