Address reprint requests to Oliver J. Warren, MRCS (Eng), Department of BioSurgery and
Surgical Technology, Imperial College London, 10th Floor QEQM Building, St Mary's …

The glycocalyx is a layer coating the luminal surface of vascular endothelial cells. It is vital
for endothelial function as it participates in microvascular reactivity, endothelium interaction …

Introduction Systemic inflammatory response syndrome is common after surgery, and it can
be difficult to discriminate between infection and inflammation. We performed a review of the …

Cardiac surgery has been routinely performed using cardiopulmonary bypass (CPB) ever
since its clinical introduction during the 1950s. CPB is, however, associated with an intense …

The systemic inflammatory response after coronary artery bypass grafting using
cardiopulmonary bypass (CPB) contributes substantially to postoperative organ dysfunction …

THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …

Cardiac surgery and cardiopulmonary bypass initiate a systemic inflammatory response
largely determined by blood contact with foreign surfaces and the activation of complement …

Background: Post-cardiac surgery renal dysfunction is a common, serious, multifactorial
disorder, with interpatient variability predicted poorly by preoperative clinical, procedural …

Cardiac surgery with cardiopulmonary bypass provokes a systemic inflammatory response
syndrome caused by the surgical trauma itself, blood contact with the non-physiological …

The endothelial glycocalyx (EG) is a gel-like layer lining the luminal surface of healthy
vascular endothelium. Recently, the EG has gained extensive interest as a crucial regulator …