Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau
A Wachter, ME Woodbury, S Lombardo… - Acta …, 2024 - Springer
Human microglia are critically involved in Alzheimer's disease (AD) progression, as shown
by genetic and molecular studies. However, their role in tau pathology progression in human …
by genetic and molecular studies. However, their role in tau pathology progression in human …
Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments
MJ Abraham, C Goncalves, P McCallum, V Gupta… - Cell & Bioscience, 2024 - Springer
Background The tumour microenvironment (TME) consists of tumour-supportive immune
cells, endothelial cells, and fibroblasts. PhenoCycler, a high-plex single cell spatial biology …
cells, endothelial cells, and fibroblasts. PhenoCycler, a high-plex single cell spatial biology …
Multiplexed, scalable, and functionality compatible platforms for 3D spatially resolved proteomic profiling
Y Tian - 2024 - dspace.mit.edu
Extracting and interpreting the network of biomolecular information is crucial for
comprehending complex biological systems. Due to the highly dynamic, deeply …
comprehending complex biological systems. Due to the highly dynamic, deeply …
Human Brain Cell Type Classification Using Spatial Proteomics
M Ellison - 2024 - search.proquest.com
Alzheimer's Disease (AD) is the most common form of dementia affecting the population
over the age of 65. AD is characterized clinically by increasing difficulty with memory and …
over the age of 65. AD is characterized clinically by increasing difficulty with memory and …