The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Gut microbiota regulation of tryptophan metabolism in health and disease
A Agus, J Planchais, H Sokol - Cell host & microbe, 2018 - cell.com
The gut microbiota is a crucial actor in human physiology. Many of these effects are
mediated by metabolites that are either produced by the microbes or derived from the …
mediated by metabolites that are either produced by the microbes or derived from the …
A tissue-like neurotransmitter sensor for the brain and gut
Neurotransmitters play essential roles in regulating neural circuit dynamics both in the
central nervous system as well as at the peripheral, including the gastrointestinal tract …
central nervous system as well as at the peripheral, including the gastrointestinal tract …
Gut enterochromaffin cells drive visceral pain and anxiety
Gastrointestinal (GI) discomfort is a hallmark of most gut disorders and represents an
important component of chronic visceral pain. For the growing population afflicted by irritable …
important component of chronic visceral pain. For the growing population afflicted by irritable …
Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks
F De Vadder, E Grasset… - Proceedings of the …, 2018 - National Acad Sciences
The enteric nervous system (ENS) is crucial for essential gastrointestinal physiologic
functions such as motility, fluid secretion, and blood flow. The gut is colonized by trillions of …
functions such as motility, fluid secretion, and blood flow. The gut is colonized by trillions of …
Tryptophan metabolism in inflammaging: from biomarker to therapeutic target
FJH Sorgdrager, PJW Naudé, IP Kema… - Frontiers in …, 2019 - frontiersin.org
Inflammation aims to restore tissue homeostasis after injury or infection. Age-related decline
of tissue homeostasis causes a physiological low-grade chronic inflammatory phenotype …
of tissue homeostasis causes a physiological low-grade chronic inflammatory phenotype …
The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine
N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
The effects of nutrition on the gastrointestinal microbiome of cats and dogs: impact on health and disease
SM Wernimont, J Radosevich, MI Jackson… - Frontiers in …, 2020 - frontiersin.org
The gastrointestinal (GI) microbiome of cats and dogs is increasingly recognized as a
metabolically active organ inextricably linked to pet health. Food serves as a substrate for …
metabolically active organ inextricably linked to pet health. Food serves as a substrate for …
Critical neurotransmitters in the neuroimmune network
TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …
express an extensive network of cell communication modes, including a vast repertoire of …
Mucosal serotonin reuptake transporter expression in irritable bowel syndrome is modulated by gut microbiota via mast cell–prostaglandin E2
J Gao, T Xiong, G Grabauskas, C Owyang - Gastroenterology, 2022 - Elsevier
Background & Aims Increased colonic serotonin (5-HT) level and decreased serotonin
reuptake transporter (SERT) expression in irritable bowel syndrome (IBS) may contribute to …
reuptake transporter (SERT) expression in irritable bowel syndrome (IBS) may contribute to …