[HTML][HTML] Chitosan in oral drug delivery formulations: A review

T Sangnim, D Dheer, N Jangra, K Huanbutta, V Puri… - Pharmaceutics, 2023 - mdpi.com
Nanoformulations have become increasingly useful as drug delivery technologies in recent
decades. As therapeutics, oral administration is the most common delivery method, although …

[HTML][HTML] Anticancer Drug Discovery based on Natural products: from computational approaches to Clinical studies

P Chunarkar-Patil, M Kaleem, R Mishra, S Ray… - Biomedicines, 2024 - mdpi.com
Globally, malignancies cause one out of six mortalities, which is a serious health problem.
Cancer therapy has always been challenging, apart from major advances in …

[HTML][HTML] A Strategy Utilizing Protein–Protein Interaction Hubs for the Treatment of Cancer Diseases

N Carels, D Sgariglia, MGV Junior, CR Lima… - International Journal of …, 2023 - mdpi.com
We describe a strategy for the development of a rational approach of neoplastic disease
therapy based on the demonstration that scale-free networks are susceptible to specific …

New Emerging Chemokine Receptors: CCR5 or CXCR5 on Tumor Is Associated with Poor Response to Chemotherapy and Poor Prognosis in Locally Advanced …

N Cabioglu, S Onder, H Karatay, A Bayram, G Oner… - Cancers, 2024 - mdpi.com
Simple Summary We investigated any possible associations between chemokine receptor
expression and responses to chemotherapy along with survival outcomes in patients with …

CRISPR/Cas9-mediated knockout strategies for enhancing immunotherapy in breast cancer

C Xu - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
Breast cancer, a prevalent disease with significant mortality rates, often presents treatment
challenges due to its complex genetic makeup. This review explores the potential of …

Prognostic and Therapeutic Implications of Cell Division Cycle 20 Homolog in Breast Cancer

SS Messeha, NO Zarmouh, H Maku, S Gendy… - Cancers, 2024 - mdpi.com
Cell division cycle 20 homolog (CDC20) is a well-known regulator of cell cycle progression.
Abnormal expression of CDC20 leads to mitotic defects, which play a significant role in …

Genome Editing: Current Approaches and the Road Ahead in Cancer Research and Therapeutics

K Athanasopoulou, GN Daneva, PG Adamopoulos… - 2024 - Springer
Genome engineering has revolutionized the landscape of molecular biology and medical
research, offering unprecedented precision in manipulating the genetic material of …

[PDF][PDF] Exploring Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR-Associated Protein 9 (CRISPR-Cas9) as a Therapeutic Modality for Cancer: A …

A Balasubramanian, K Veluswami, S Rao, S Aggarwal… - Cureus, 2024 - cureus.com
The global burden of cancer and the limitations of conventional therapies highlight the
potential of clustered regularly interspaced short palindromic repeats-CRISPR-associated …