Post-transcriptional regulation is a very important mechanism to control gene expression in
changing environments. In the past decade, a lot of interest has been directed toward the …

The Lyme disease spirochete persists in nature through cycles between ticks and
vertebrates. Although the spirochete interacts with numerous, distinct tissues and …

B orrelia burgdorferi, the agent of L yme disease, is maintained in nature within an enzootic
cycle involving a mammalian reservoir and an I xodes sp. tick vector. The transmission …

Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …

Borrelia burgdorferi, the agent of Lyme disease, differentially expresses numerous genes
and proteins as it cycles between mammalian hosts and tick vectors. Insights on regulatory …

The PilZ domain‐containing protein, PlzA, is the only known cyclic di‐GMP binding protein
encoded by all Lyme disease spirochetes. PlzA has been implicated in the regulation of …

Lyme disease is the most common vector-borne disease in the northern hemisphere and is
caused by spirochetes of the Borrelia burgdorferi sensu lato complex. Lyme borreliae infect …

ABSTRACT The Lyme disease spirochete, Borrelia burgdorferi, persists in nature by
alternatingly cycling between ticks and vertebrates. During each stage of the infectious …

The infectious cycle of Borrelia burgdorferi necessitates persistent infection of both
vertebrates and ticks, and efficient means of transmission between those two very different …

Borrelia burgdorferi, the causative agent of Lyme disease, survives in nature through a cycle
that alternates between ticks and vertebrates. To facilitate this defined lifestyle, B. burgdorferi …