Recent advances in sustainable synthesis of N-heterocycles following acceptorless dehydrogenative coupling protocol using alcohols

M Maji, D Panja, I Borthakur, S Kundu - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The synthesis of heterocycles is an emerging area of chemical research considering their
high importance in pharmaceuticals, material chemistry, and natural product synthesis. The …

Cobalt-catalyzed dehydrogenative functionalization of alcohols: progress and future prospect

I Borthakur, A Sau, S Kundu - Coordination Chemistry Reviews, 2022 - Elsevier
Functionalization of alcohol is a promising field in synthesis for the possible conservation of
fossil-based-feedstocks, since alcohols can be easily obtained from readily available …

Borrowing Hydrogen β-Phosphinomethylation of Alcohols Using Methanol as C1 Source by Pincer Manganese Complex

F Sun, X Chen, S Wang, F Sun… - Journal of the American …, 2023 - ACS Publications
Herein, we report a manganese-catalyzed three-component coupling of β-H containing
alcohols, methanol, and phosphines for the synthesis of γ-hydroxy phosphines via a …

Multifunctional catalysis of nanosheet defective molybdenum sulfide basal planes for tandem reactions involving alcohols and molecular hydrogen

M Rodenes, F Dhaeyere, S Martín… - ACS Sustainable …, 2023 - ACS Publications
Establishing tandem catalytic synthetic strategies based on the use of readily available,
stable, and renewable feedstocks is of great significant for the sustainable advancement of …

Dehydrogenative synthesis of quinolines and quinazolines via ligand-free cobalt-catalyzed cyclization of 2-aminoaryl alcohols with ketones or nitriles

Z Hao, X Zhou, Z Ma, C Zhang, Z Han… - The Journal of Organic …, 2022 - ACS Publications
We present a convenient and efficient protocol to synthesize quinolines and quinazolines in
one pot under mild conditions. A variety of substituted quinolines were synthesized in good …

Borrowing Hydrogen and Acceptorless Dehydrogenative Coupling in the Multicomponent Synthesis of N‐Heterocycles: A Comparison between Base and Noble Metal …

N Hofmann, KC Hultzsch - European Journal of Organic …, 2021 - Wiley Online Library
Acceptorless dehydrogenative coupling reactions (ADC) and hydrogen transfer strategies
(HT) provide a powerful tool in the multicomponent formation of N‐heterocycles. A broad …

Manganese (I)-catalyzed sustainable synthesis of quinoxaline and quinazoline derivatives with the liberation of dihydrogen

A Mondal, MK Sahoo, M Subaramanian… - The Journal of …, 2020 - ACS Publications
Direct synthesis of N-heterocycles via the acceptorless dehydrogenative coupling is very
challenging and scarcely reported under 3d transition-metal catalysis. Here, we have …

Novel methodologies for chemical activation in organic synthesis under solvent-free reaction conditions

CG Avila-Ortiz, E Juaristi - Molecules, 2020 - mdpi.com
One central challenge for XXI century chemists is the development of sustainable processes
that do not represent a risk either to humanity or to the environment. In this regard, the …

Simple RuCl3‐catalyzed N‐Methylation of Amines and Transfer Hydrogenation of Nitroarenes using Methanol

N Sarki, V Goyal, NK Tyagi, Puttaswamy… - …, 2021 - Wiley Online Library
Methanol is a potential hydrogen source and C1 synthon, which finds interesting
applications in both chemical synthesis and energy technologies. The effective utilization of …

Ruthenium Pincer Complex Catalyzed Selective Synthesis of C‐3 Alkylated Indoles and Bisindolylmethanes Directly from Indoles and Alcohols

N Biswas, R Sharma, D Srimani - Advanced Synthesis & …, 2020 - Wiley Online Library
Herein, we presented Ru‐SNS complex that serves as a useful catalyst for C‐3 alkylation of
1H‐indoles with various aliphatic primary and secondary alcohols including cyclic alcohols …