Medicinal plants used in the treatment of Malaria: A key emphasis to Artemisia, Cinchona, Cryptolepis, and Tabebuia genera
Malaria is one of the life‐threatening parasitic diseases that is endemic in tropical areas. The
increased prevalence of malaria due to drug resistance leads to a high incidence of …
increased prevalence of malaria due to drug resistance leads to a high incidence of …
Molecular insights into the interaction of RONS and Thieno [3, 2-c] pyran analogs with SIRT6/COX-2: A molecular dynamics study
SIRT6 and COX-2 are oncogenes target that promote the expression of proinflammatory and
pro-survival proteins through a signaling pathway, which leads to increased survival and …
pro-survival proteins through a signaling pathway, which leads to increased survival and …
Influence of reactive species on the modification of biomolecules generated from the soft plasma
Plasma medicine is an upcoming research area that has attracted the scientists to explore
more deeply the utility of plasma. So, apart from the treating biomaterials and tissues with …
more deeply the utility of plasma. So, apart from the treating biomaterials and tissues with …
Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay
In this study, pharmacophore based 3D QSAR models for human acetylcholinesterase
(AChE) inhibitors were generated, with good significance, statistical values (r2training …
(AChE) inhibitors were generated, with good significance, statistical values (r2training …
Multiple QSAR and molecular modelling for identification of potent human adenovirus inhibitors
SN Mali, A Pandey - Journal of the Indian Chemical Society, 2021 - Elsevier
This study has investigated docking-based 2D-and 3D-quantitative structure-activity
relationships (QSARs) for a range of 53 hydroxybenzamide analogues as anti-Human …
relationships (QSARs) for a range of 53 hydroxybenzamide analogues as anti-Human …
Molecular docking, QSAR and ADMET studies of withanolide analogs against breast cancer
Withanolides are a group of pharmacologically active compounds present in most prodigal
amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most …
amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most …
Synergy of clavine alkaloid 'chanoclavine' with tetracycline against multi-drug-resistant E. coli
The emergence of multi drug resistance (MDR) in Gram-negative bacteria (GNB) and lack of
novel classes of antibacterial agents have raised an immediate need to identify antibacterial …
novel classes of antibacterial agents have raised an immediate need to identify antibacterial …
New arylated benzo[h]quinolines induce anti-cancer activity by oxidative stress-mediated DNA damage
The anti-cancer activity of the benzo [h] quinolines was evaluated on cultured human skin
cancer (G361), lung cancer (H460), breast cancer (MCF7) and colon cancer (HCT116) cell …
cancer (G361), lung cancer (H460), breast cancer (MCF7) and colon cancer (HCT116) cell …
Synthesis of michael adducts as key building blocks for potential analgesic drugs: in vitro, in vivo and in silico explorations
Background Organocatalytic asymmetric Michael addition is a strong approach for CC bond
formation. The objective of the study is to design molecules by exploiting the efficiency of …
formation. The objective of the study is to design molecules by exploiting the efficiency of …
Induced apoptosis in melanocytes cancer cell and oxidation in biomolecules through deuterium oxide generated from atmospheric pressure non-thermal plasma jet
Recently, atmospheric-pressure non-thermal plasma-jets (APPJ) are being for the cancer
treatment. However, APPJ still has drawbacks such as efficiency and rise in temperature …
treatment. However, APPJ still has drawbacks such as efficiency and rise in temperature …