Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …

A healthy nutritional state is required for all aspects of reproduction and is signaled by the
adipokine leptin. Leptin acts in a relatively narrow concentration range: too much or too little …

The concept emerging from Professor David Barker's seminal research on the
developmental origins of later-life disease has progressed in many directions since it was …

A minimum amount of energy is required for basic physiological processes, such as protein
biosynthesis, thermoregulation, locomotion, cardiovascular function, and digestion …

Aims Diets containing high‐fat and high sugar (HFHS) lead to overweight/obesity.
Overweight/obesity increases the risk of infertility, and of the pregnant mother and her child …

Per-and polyfluoroalkyl substances (PFAS) are a family of chemicals that are ubiquitous in
the environment. Some of these chemicals, such as perfluorooctanesulfonic acid (PFOS) …

The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

Obesity during pregnancy is a known health risk for mother and child. Since obesity is
associated with increased inflammatory markers, our objectives were to determine …

Maternal high-fat diet (HFD) often results in intrauterine and feto-placental inflammation, and
increases the risks of fetal programming of metabolic diseases. Intake of prebiotic is reported …

Maternal obesity is a serious health concern because it increases risks of neurological
disorders, including anxiety and peripartum depression. In mice, a high fat diet (HFD) in …