New perspectives on antimicrobial agents: isavuconazole

JS Lewis, NP Wiederhold, M Hakki… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Isavuconazole is the newest of the clinically available advanced generation triazole
antifungals and is active against a variety of yeasts, molds, and dimorphic fungi. Its current …

Recent advances and future directions in the understanding of mucormycosis

V Garre - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Mucormycosis is an emerging infection caused by fungi of the order Mucorales that has
recently gained public relevance due to the high incidence among COVID-19 patients in …

Construction of canthaxanthin-producing yeast by combining spatiotemporal regulation and pleiotropic drug resistance engineering

M Chen, M Li, L Ye, H Yu - ACS Synthetic Biology, 2021 - ACS Publications
The ketocarotenoid canthaxanthin has important applications in the feed industry. Its
biosynthesis using microbial cell factories is an attractive alternative to the current chemical …

Molecular mechanisms that govern infection and antifungal resistance in Mucorales

C Lax, FE Nicolás, E Navarro… - … and Molecular Biology …, 2024 - Am Soc Microbiol
SUMMARY The World Health Organization has established a fungal priority pathogens list
that includes species critical or highly important to human health. Among them is the order …

A Comprehensive in vitro and in silico Assessment on Inhibition of CYP51B and Ergosterol Biosynthesis by Eugenol in Rhizopus oryzae

J Prajapati, P Rao, L Poojara, D Acharya, SK Patel… - Current …, 2023 - Springer
Mucormycosis, also known as Zygomycosis, is a disease caused by invasive fungi,
predominantly Rhizopus species belonging to the Order of Mucorales. Seeing from the …

Promising Antifungal Molecules against Mucormycosis Agents Identified from Pandemic Response Box®: In Vitro and In Silico Analyses

MIDS Xisto, R Rollin-Pinheiro, Y de Castro-Almeida… - Journal of Fungi, 2023 - mdpi.com
Mucormycosis is considered concerning invasive fungal infections due to its high mortality
rates, difficult diagnosis and limited treatment approaches. Mucorales species are highly …

Miltefosine: a repurposing drug against Mucorales pathogens

MIDS Xisto, R Rollin-Pinheiro, VP Rochetti… - Journal of Fungi, 2023 - mdpi.com
Mucorales are a group of non-septated filamentous fungi widely distributed in nature,
frequently associated with human infections, and are intrinsically resistant to many …

Characterization of the Sterol 24-C-Methyltransferase Genes Reveals a Network of Alternative Sterol Biosynthetic Pathways in Mucor lusitanicus

K Bauer, B Rafael, B Vágó, S Kiss-Vetráb… - Microbiology …, 2023 - Am Soc Microbiol
Certain members of the order Mucorales can cause a life-threatening, often-fatal systemic
infection called mucormycosis. Mucormycosis has a high mortality rate, which can reach 96 …

[HTML][HTML] Effectiveness of front line and emerging fungal disease prevention and control interventions and opportunities to address appropriate eco-sustainable …

M Garvey, E Meade, NJ Rowan - Science of the Total Environment, 2022 - Elsevier
Fungal pathogens contribute to significant disease burden globally; however, the fact that
fungi are eukaryotes has greatly complicated their role in fungal-mediated infections and …

Advances in understanding infections caused by the basal fungus Mucor

JT Cánovas-Márquez, C Lax, G Tahiri, E Navarro… - PLoS …, 2023 - journals.plos.org
AU: Pleaseconfirmthatallheadinglevelsarerepre…. Mucormycosis represents a group of
infections with different organ manifestations caused by some species of the fungal order …