[HTML][HTML] Oxidative stress and the amyloid beta peptide in Alzheimer's disease

C Cheignon, M Tomas, D Bonnefont-Rousselot… - Redox biology, 2018 - Elsevier
Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

Amyloidosis in Alzheimer's disease: Pathogeny, etiology, and related therapeutic directions

C Ma, F Hong, S Yang - Molecules, 2022 - mdpi.com
The amyloid hypothesis of Alzheimer's disease has long been the predominant theory,
suggesting that Alzheimer's disease is caused by the accumulation of amyloid beta protein …

Multi-modality cascaded convolutional neural networks for Alzheimer's disease diagnosis

M Liu, D Cheng, K Wang, Y Wang… - Neuroinformatics, 2018 - Springer
Accurate and early diagnosis of Alzheimer's disease (AD) plays important role for patient
care and development of future treatment. Structural and functional neuroimages, such as …

The impact of the CX3CL1/CX3CR1 axis in neurological disorders

P Pawelec, M Ziemka-Nalecz, J Sypecka, T Zalewska - Cells, 2020 - mdpi.com
Fractalkine (FKN, CX3CL1) is a transmembrane chemokine expressed by neurons in the
central nervous system (CNS). CX3CL1 signals through its unique receptor, CX3CR1, that is …

[HTML][HTML] Autophagy and apoptosis dysfunction in neurodegenerative disorders

S Ghavami, S Shojaei, B Yeganeh, SR Ande… - Progress in …, 2014 - Elsevier
Autophagy and apoptosis are basic physiologic processes contributing to the maintenance
of cellular homeostasis. Autophagy encompasses pathways that target long-lived cytosolic …

Deep learning framework for Alzheimer's disease diagnosis via 3D-CNN and FSBi-LSTM

C Feng, A Elazab, P Yang, T Wang, F Zhou, H Hu… - IEEE …, 2019 - ieeexplore.ieee.org
Alzheimer's disease (AD) is an irreversible progressive neurodegenerative disorder. Mild
cognitive impairment (MCI) is the prodromal state of AD, which is further classified into a …

Classification of Alzheimer's disease by combination of convolutional and recurrent neural networks using FDG-PET images

M Liu, D Cheng, W Yan… - Frontiers in …, 2018 - frontiersin.org
Alzheimer's disease (AD) is an irreversible brain degenerative disorder affecting people
aged older than 65 years. Currently, there is no effective cure for AD, but its progression can …

In vitro enzymatic evaluation of some pyrazolo[1,5‐a]pyrimidine derivatives: Design, synthesis, antioxidant, anti‐diabetic, anti‐Alzheimer, and anti‐arthritic activities …

AS Hassan, NM Morsy… - Drug Development …, 2023 - Wiley Online Library
The strategy of utilizing nitrogen compounds in various biological applications has recently
emerged as a powerful approach to exploring novel classes of therapeutics to face the …

Anti-Alzheimer's Studies on β-Sitosterol Isolated from Polygonum hydropiper L.

M Ayaz, M Junaid, F Ullah, F Subhan, A Sadiq… - Frontiers in …, 2017 - frontiersin.org
The family Polygonaceae is known for its traditional use in the management of various
neurological disorders including Alzheimer's disease (AD). In search of new anti-AD drugs …

Resting-state brain networks: literature review and clinical applications

C Rosazza, L Minati - Neurological sciences, 2011 - Springer
This review focuses on resting-state functional connectivity, a functional MRI technique
which allows the study of spontaneous brain activity generated under resting conditions …