The amyloid hypothesis of Alzheimer's disease has long been the predominant theory, suggesting that Alzheimer's disease is caused by the accumulation of amyloid beta protein …
M Liu, D Cheng, K Wang, Y Wang… - Neuroinformatics, 2018 - Springer
Accurate and early diagnosis of Alzheimer's disease (AD) plays important role for patient care and development of future treatment. Structural and functional neuroimages, such as …
P Pawelec, M Ziemka-Nalecz, J Sypecka, T Zalewska - Cells, 2020 - mdpi.com
Fractalkine (FKN, CX3CL1) is a transmembrane chemokine expressed by neurons in the central nervous system (CNS). CX3CL1 signals through its unique receptor, CX3CR1, that is …
Autophagy and apoptosis are basic physiologic processes contributing to the maintenance of cellular homeostasis. Autophagy encompasses pathways that target long-lived cytosolic …
Alzheimer's disease (AD) is an irreversible progressive neurodegenerative disorder. Mild cognitive impairment (MCI) is the prodromal state of AD, which is further classified into a …
M Liu, D Cheng, W Yan… - Frontiers in …, 2018 - frontiersin.org
Alzheimer's disease (AD) is an irreversible brain degenerative disorder affecting people aged older than 65 years. Currently, there is no effective cure for AD, but its progression can …
AS Hassan, NM Morsy… - Drug Development …, 2023 - Wiley Online Library
The strategy of utilizing nitrogen compounds in various biological applications has recently emerged as a powerful approach to exploring novel classes of therapeutics to face the …
M Ayaz, M Junaid, F Ullah, F Subhan, A Sadiq… - Frontiers in …, 2017 - frontiersin.org
The family Polygonaceae is known for its traditional use in the management of various neurological disorders including Alzheimer's disease (AD). In search of new anti-AD drugs …
This review focuses on resting-state functional connectivity, a functional MRI technique which allows the study of spontaneous brain activity generated under resting conditions …