Neopterin, inflammation, and oxidative stress: what could we be missing?

SP Gieseg, G Baxter-Parker, A Lindsay - Antioxidants, 2018 - mdpi.com
Neopterin has been extensively used as a clinical marker of immune activation during
inflammation in a wide range of conditions and stresses. However, the analysis of neopterin …

[HTML][HTML] Circulating biomarkers in lower extremity artery disease

L Ziegler, U Hedin, A Gottsäter - European Cardiology Review, 2022 - ncbi.nlm.nih.gov
Lower extremity artery disease (LEAD), a chronic condition with disturbed lower extremity
circulation due to narrowing of the arteries, is predominantly caused by atherosclerosis and …

Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia Exposure

C Leveque, S Mrakic Sposta, S Theunissen… - International journal of …, 2023 - mdpi.com
In this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of
10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 …

Biomarker utility for peripheral artery disease diagnosis in real clinical practice: A prospective study

A Ceasovschih, V Sorodoc, V Onofrei, D Tesloianu… - Diagnostics, 2020 - mdpi.com
Peripheral arterial disease (PAD) is a common manifestation of generalized atherosclerosis,
which affects more than 200 million patients worldwide. Currently, there is no ideal …

Neopterin, the cell-mediated immune response biomarker, in inflammatory periodontal diseases: a narrative review of a more than fifty years old biomarker

O Heneberk, E Wurfelova, V Radochova - Biomedicines, 2023 - mdpi.com
Neopterin is a biomarker of the activation of cellular immunity. The purpose of this review is
to summarise neopterin metabolism, methods of its detection, and its role in inflammation …

CD36 down regulation by the macrophage antioxidant 7, 8-dihydroneopterin through modulation of PPAR-γ activity

N Ghodsian, A Yeandle, BD Hock… - Free Radical …, 2022 - Taylor & Francis
CD36 is the key scavenger receptor driving the formation of cholesterol-loaded foam cells,
the principal cellular component of atherosclerotic plaques. CD36 is down regulated by 7, 8 …

New Insights in Prevention and Treatment of Cardiovascular Disease

D Di Raimondo, G Musiari, G Rizzo, E Pirera… - International journal of …, 2022 - mdpi.com
Cardiovascular (CV) disease (CVD) is still a major cause of morbidity and mortality in many
countries in Europe although considerable efforts have been made in recent decades to …

Narrative Review of Biological Markers in Chronic Limb-Threatening Ischemia

AI Popescu, AL Rata, S Barac, R Popescu, RR Onofrei… - Biomedicines, 2024 - mdpi.com
Background: Chronic limb-threatening ischemia (CLTI), the advanced stage of peripheral
arterial disease, is diagnosed in the presence of ischemic rest pain, non-healing ulcers, or …

Assessment of serum neopterin as a biomarker in peripheral artery disease

A Zembron-Lacny, W Dziubek, A Tylutka, E Wacka… - Diagnostics, 2021 - mdpi.com
Neopterin (NPT), a pyrazino-pyrimidine compound mainly produced by activated
macrophages, has been regarded as a proinflammatory and proatherosclerotic agent. The …

Effect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial

A Helland, M Bratlie, IV Hagen, Ø Midttun… - European Journal of …, 2021 - Springer
Purpose Primarily, to investigate the effect of high intake of cod (lean fish) or salmon (fatty
fish) on serum concentration of total neopterin, a marker of cellular immune activation that is …