Carriers of the p. P522R variant in PLCγ2 have a slightly more responsive immune system

AM Diks, C Teodosio, B de Mooij, RJ Groenland… - Molecular …, 2023 - Springer
Background The rs72824905 single-nucleotide polymorphism in the PLCG2 gene, encoding
the p. P522R residue change in Phospholipase C gamma 2 (PLCγ2), associates with …

The association of microbial infection and adaptive immune cell activation in Alzheimer's disease

M Clement - Discovery Immunology, 2023 - academic.oup.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common form of dementia. Early symptoms include the loss of memory and mild cognitive …

[HTML][HTML] The genetic overlap between Alzheimer's disease, amyotrophic lateral sclerosis, Lewy body dementia, and Parkinson's disease

DP Wightman, JE Savage, E Tissink, C Romero… - Neurobiology of …, 2023 - Elsevier
Neurodegenerative diseases are a group of disorders characterized by neuronal cell death
causing a variety of physical and mental problems. While these disorders can be …

HLA in isolated REM sleep behavior disorder and Lewy body dementia

E Yu, L Krohn, JA Ruskey, F Asayesh… - Annals of Clinical …, 2023 - Wiley Online Library
Synucleinopathies‐related disorders such as Lewy body dementia (LBD) and
isolated/idiopathic REM sleep behavior disorder (iRBD) have been associated with …