Growing evidence suggests that neuroinflammation is not just a consequence of
neurodegeneration in pathologies such as Alzheimer's disease, Parkinson's disease …

The effect of the modulators of the mitochondrial ATP-dependent potassium channel
(mitoKATP) on the structural and biochemical alterations in the substantia nigra and brain …

Biological and scarce epidemiological evidence suggested that phosphodiesterase-5
inhibitors (PDE5i) might reduce dementia risk. We aimed to examine the association …

Pharmacoepidemiologic studies using routinely collected data allow researchers to propose
drugs for repurposing trials for dementia prevention or treatment. A recent cohort study …

Although high-throughput DNA/RNA sequencing technologies have generated massive
genetic and genomic data in human disease, these findings have not been translated into …

Protein misfolding and aggregation into cytotoxic amyloid plays an important role in the
pathogenesis of various neurodegenerative diseases including Alzheimer's Disease (AD) …

Dementia is currently the seventh leading cause of death, and one of the major causes of
disability and dependency among older people globally. Behavioural and psychological …