Importance Patients aged 80 years and older were often excluded or underrepresented in
pivotal endovascular thrombectomy (EVT) trials. Accordingly, trends in frequency, outcomes …

Background: With ideal mean arterial pressure (MAP) targets in resuscitated out-of-hospital
cardiac arrest (OHCA) patients unknown, we performed a meta-analysis of randomised …

Importance The effectiveness and safety of intravenous alteplase given before or
concurrently with endovascular thrombectomy (EVT) is uncertain. Randomized clinical trials …

Background Automated infrared pupillometry (AIP) and the Neurological Pupil index (NPi)
provide an objective means of assessing and trending the pupillary light reflex (PLR) across …

The landscape of acute ischemic stroke management has undergone a substantial
transformation over the past 3 decades, mirroring our enhanced comprehension of the …

Background: Existing data and clinical trials could not determine whether faster intravenous
thrombolytic therapy (IVT) translates into better long-term functional outcomes after acute …

Background Stroke is a significant global health burden and ranks as the second leading
cause of death worldwide. Objective This study aims to develop and evaluate a machine …

Background and aim Recent studies have shown that the CT Perfusion (CTP) parameter of
rCBV< 42% lesion volume can predict 90-day functional outcomes in stroke patients …

Objective To evaluate clinical outcomes of endovascular thrombectomy (EVT) for acute
basilar artery occlusion (BAO) using population‐level data from the United States. Methods …

Importance Clinical trials have suggested that prehospital management in a mobile stroke
unit (MSU) improves functional outcomes in patients with acute ischemic stroke who are …