Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Genomics of disease risk in globally diverse populations

D Gurdasani, I Barroso, E Zeggini… - Nature Reviews …, 2019 - nature.com
Risk of disease is multifactorial and can be shaped by socio-economic, demographic,
cultural, environmental and genetic factors. Our understanding of the genetic determinants …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Genomic insights into the formation of human populations in East Asia

CC Wang, HY Yeh, AN Popov, HQ Zhang… - Nature, 2021 - nature.com
The deep population history of East Asia remains poorly understood owing to a lack of
ancient DNA data and sparse sampling of present-day people,. Here we report genome …

[HTML][HTML] Population genomics of post-glacial western Eurasia

ME Allentoft, M Sikora, A Refoyo-Martínez… - Nature, 2024 - nature.com
Western Eurasia witnessed several large-scale human migrations during the Holocene,,,–.
Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced …

Ancient DNA indicates human population shifts and admixture in northern and southern China

MA Yang, X Fan, B Sun, C Chen, J Lang, YC Ko… - Science, 2020 - science.org
Human genetic history in East Asia is poorly understood. To clarify population relationships,
we obtained genome-wide data from 26 ancient individuals from northern and southern East …

The deep population history of northern East Asia from the Late Pleistocene to the Holocene

X Mao, H Zhang, S Qiao, Y Liu, F Chang, P Xie… - Cell, 2021 - cell.com
Summary Northern East Asia was inhabited by modern humans as early as 40 thousand
years ago (ka), as demonstrated by the Tianyuan individual. Using genome-wide data …

Anthropogenic impacts on Late Holocene land-cover change and floristic biodiversity loss in tropical southeastern Asia

Z Zheng, T Ma, P Roberts, Z Li, Y Yue… - Proceedings of the …, 2021 - National Acad Sciences
Southern China and Southeast Asia witnessed some of their most significant economic and
social changes relevant to human land use during the Late Holocene, including the …

Extraction of highly degraded DNA from ancient bones, teeth and sediments for high-throughput sequencing

N Rohland, I Glocke, A Aximu-Petri, M Meyer - Nature protocols, 2018 - nature.com
DNA preserved in ancient bones, teeth and sediments is typically highly fragmented and
present only in minute amounts. Here, we provide a highly versatile silica-based DNA …

Genomic history and ecology of the geographic spread of rice

RM Gutaker, SC Groen, ES Bellis, JY Choi, IS Pires… - Nature plants, 2020 - nature.com
Rice (Oryza sativa) is one of the world's most important food crops, and is comprised largely
of japonica and indica subspecies. Here, we reconstruct the history of rice dispersal in Asia …