Chiral nanomaterials with intrinsic chirality or spatial asymmetry at the nanoscale are
currently in the limelight of both fundamental research and diverse important technological …

A hallmark event in neurodegenerative diseases (NDs) is the misfolding, aggregation, and
accumulation of proteins, leading to cellular dysfunction, loss of synaptic connections, and …

The aggregation of proteins into amyloid fibrils and their deposition into plaques and
intracellular inclusions is the hallmark of amyloid disease. The accumulation and deposition …

Hierarchical self-assembly and crystallization with long-range ordered spatial arrangement
is ubiquitous in nature and plays an essential role in the regulation of structures and …

Alzheimer's disease is the most common neurodegenerative disease, and there are no
mechanism-based therapies. The disease is defined by the presence of abundant …

Misfolding and aggregation of disease-specific proteins, resulting in the formation of
filamentous cellular inclusions, is a hallmark of neurodegenerative disease with …

This review will focus on the process of amyloid-type protein aggregation. Amyloid fibrils are
an important hallmark of protein misfolding diseases and therefore have been investigated …

Peptides and proteins have been found to possess an inherent tendency to convert from
their native functional states into intractable amyloid aggregates. This phenomenon is …

Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …

Tau aggregation into insoluble filaments is the defining pathological hallmark of tauopathies.
However, it is not known what controls the formation and templated seeding of strain-specific …