Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass
and microstructure, leading to reduced bone strength and increased risk of fracture. It is …

Osteoporosis is an asymptomatic progressive disease. With the improvement of people's
living standard and the aging of population, osteoporosis and its fracture have become one …

Background Female age-related estrogen deficiency increases the risk of osteoporosis,
which can be effectively treated with the use of hormone replacement therapy. However …

Isoflavones, a group of flavonoids, restricted almost exclusively to family Leguminosae are
known to exhibit anticancerous and anti‐osteoporotic activities in animal systems and have …

Glucocorticoid-induced osteoporosis (GIOP) is a common clinical consequence that arises
due to the extensive usage of glucocorticoids. Cladrin (Clad), a methoxylated isoflavone has …

Introduction Gut microbiota (GM) is the collection of small organisms such as bacteria, fungi,
bacteriophages and protozoans living in the intestine in symbiotics relation within their host …

Background Cancer is one of the leading causes of death and a great threat to people
around the world. Cancer treatment modalities include surgery, radiotherapy, chemotherapy …

It is widely accepted that physiological mechanical stimulation suppresses apoptosis and
induces synthesis of extracellular matrix by osteoblasts; however, the effect of stress …

TNF-α is known to induce osteoblasts apoptosis, whereas mechanical stimulation has been
shown to enhance osteoblast survival. In the present study, we found that mechanical …

Daidzein, a natural soy isoflavone, has a structure similar to estradiol and exhibiting bone-
sparing effects against osteoporosis. However, the molecular mechanisms of osteogenesis …