Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …

The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …

A long-standing hypothesis termed “Hebbian plasticity” suggests that memories are formed
through strengthening of synaptic connections between neurons with correlated activity. In …

Throughout life animals learn to recognize cues that signal danger and instantaneously
initiate an adequate threat response. Memories of such associations may last a lifetime and …

Temporal lobe studies in motor neuron disease overwhelmingly focus on white matter
alterations and cortical grey matter atrophy. Reports on amygdala involvement are …

Memories of threatening, fear-evoking events can persist even over a lifetime. While fear
memory is widely considered to be a highly persistent and durable form of memory, its …

Research in fear conditioning has provided a comprehensive picture of the neuronal circuit
underlying the formation of fear memories. In contrast, our understanding of the retrieval of …

The amygdala-prefrontal-cortex circuit has long occupied the center of the threat system, 1
but new evidence has rapidly amassed to implicate threat processing outside this canonical …

Emotional memories represent the core of human and animal life and drive future choices
and behaviors. Early research involving brain lesion studies in animals lead to the idea that …

In Pavlovian fear conditioning, the lateral amygdala (LA) has been highlighted as a key
brain site for association between sensory cues and aversive stimuli. However, learning …