Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
VS Sohal, JLR Rubenstein - Molecular psychiatry, 2019 - nature.com
Abstract In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD)
might be caused by a reduction in signal-to-noise in key neural circuits, which could be the …
might be caused by a reduction in signal-to-noise in key neural circuits, which could be the …
Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications
The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors
including social communication and stereotypies. In addition to genetic risks, the gut …
including social communication and stereotypies. In addition to genetic risks, the gut …
A systematic comparison of neurotoxicity of bisphenol A and its derivatives in zebrafish
J Gu, M Guo, X Yin, C Huang, L Qian, L Zhou… - Science of the Total …, 2022 - Elsevier
As more and more countries have prohibited the manufacture and sale of plastic products
with bisphenol A (BPA), a number of bisphenol analogues (BPs), including BPS, BPF and …
with bisphenol A (BPA), a number of bisphenol analogues (BPs), including BPS, BPF and …
Neurotoxicity of polystyrene nanoplastics with different particle sizes at environment-related concentrations on early zebrafish embryos
R Zhou, D Zhou, S Yang, Z Shi, H Pan, Q Jin… - Science of The Total …, 2023 - Elsevier
Nanoplastics (NPs) have received global attention due to their wide application and
detection in various environmental or biological media. NPs can penetrate physical barriers …
detection in various environmental or biological media. NPs can penetrate physical barriers …
Circuitry underlying experience-dependent plasticity in the mouse visual system
BM Hooks, C Chen - Neuron, 2020 - cell.com
Since the discovery of ocular dominance plasticity, neuroscientists have understood that
changes in visual experience during a discrete developmental time, the critical period …
changes in visual experience during a discrete developmental time, the critical period …
Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale
The gabapentinoids, gabapentin, and pregabalin, target the α2δ subunits of voltage-gated
calcium channels. Initially licensed for pain and seizures, they have become widely …
calcium channels. Initially licensed for pain and seizures, they have become widely …
A review of decreased sound tolerance in autism: Definitions, phenomenology, and potential mechanisms
Atypical behavioral responses to environmental sounds are common in autistic children and
adults, with 50–70% of this population exhibiting decreased sound tolerance (DST) at some …
adults, with 50–70% of this population exhibiting decreased sound tolerance (DST) at some …
Autism spectrum disorder: focus on glutamatergic neurotransmission
M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
Distinct patterns of neural habituation and generalization in children and adolescents with autism with low and high sensory overresponsivity
Objective: Sensory overresponsivity (SOR), an atypical negative reaction to sensory stimuli,
is highly prevalent in autism spectrum disorder (ASD). Previous work has related SOR to …
is highly prevalent in autism spectrum disorder (ASD). Previous work has related SOR to …