Elevated serum uric acid is a marker for decreased renal function, may have a mechanistic
role in the incidence and progression of renal functional decline and likely has a causal role …

Despite advances in the management of patients with diabetes, diabetic nephropathy (DN)
remains the most common cause of end-stage renal disease in the United States and …

Results In all subjects, the mean uric acid level was 7.9±2.0 mg/dl. During a median 2.8-year
follow-up, there were 471 (14.3%) deaths, 545 (16.5%) cardiovascular events, 1080 (32.3%) …

Current evidence supports the role of uric acid as marker and mediator of risk for both
hypertension and progressive decline in renal function. Data on the impact of xanthine …

Background There are inconsistent findings on the role of hyperuricemia as an independent
risk factor for chronic kidney disease (CKD). Hypertension has been implicated as a factor …

Aim Inconsistent investigations of the risk factors for all-cause mortality in patients
undergoing peritoneal dialysis (PD) were reported. The present meta-analysis aimed to …

After uric acid was recognized as the causative factor in gout, increased prevalence of renal
disease and hypertension in this patient population caught the attention of the medical …

Background Although serum uric acid level appears to be associated with mortality in
individuals treated with hemodialysis, the relationship between serum uric acid level and …

Uric acid‐mediated biological effects are milieu dependent. In a physiological milieu, serum
uric acid serves as an antioxidant; when homeostasis is perturbed, divergent effects are …

Background. Kidney disease is commonly accompanied by hyperuricemia. However, the
contribution of serum uric acid (SUA) to kidney injury is debated. Our objective was to …