Innovations towards sustainable olive crop management: a new dawn by precision agriculture including endo-therapy

L Grandi, M Oehl, T Lombardi, VR De Michele… - Frontiers in Plant …, 2023 - frontiersin.org
Olive trees (Olea europaea L.) are deeply interwoven with the past, present and future of
Mediterranean civilizations, both as essential economical as well as cultural valuables. Olive …

Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels

J Veiga-Matos, AI Morales, M Prieto, F Remião, R Silva - Molecules, 2023 - mdpi.com
P-glycoprotein (P-gp) is a crucial membrane transporter situated on the cell's apical surface,
being responsible for eliminating xenobiotics and endobiotics. P-gp modulators are …

EpiMed Coronabank Chemical Collection: Compound selection, ADMET analysis, and utilisation in the context of potential SARS-CoV-2 antivirals

E Pitsillou, RC Beh, JJ Liang, TS Tang, X Zhou… - Journal of Molecular …, 2023 - Elsevier
Antiviral drugs are important for the coronavirus disease 2019 (COVID-19) response, as
vaccines and antibodies may have reduced efficacy against severe acute respiratory …

[HTML][HTML] Investigation of the Anti-Inflammatory Properties of Bioactive Compounds from Olea europaea: In Silico Evaluation of Cyclooxygenase Enzyme Inhibition and …

TC Karagiannis, K Ververis, JJ Liang, E Pitsillou… - Molecules, 2024 - mdpi.com
In a landmark study, oleocanthal (OLC), a major phenolic in extra virgin olive oil (EVOO),
was found to possess anti-inflammatory activity similar to ibuprofen, involving inhibition of …

Novel design of fractional cholesterol dynamics and drug concentrations model with analysis on machine predictive networks

MJAA Raja, SA Hassan, CY Chang, H Raza… - Computers in Biology …, 2025 - Elsevier
Within the intricate fabric of human physiology, cholesterol, a lipid present in cell
membranes exerts a discernible effect on the concentration of the drug in human body that …

Economic sustainability assessment of Mediterranean crops: A comparative Life Cycle Costing (LCC) analysis

E Spada, T Stillitano, G Falcone, N Iofrida… - … in Sustainable Food …, 2022 - frontiersin.org
The production of food with beneficial health effects is at the attention of consumer
entrepreneurs and public decision-makers. Plants with established health benefits such as …

[HTML][HTML] An In Silico Investigation of the Pathogenic G151R G Protein-Gated Inwardly Rectifying K+ Channel 4 Variant to Identify Small Molecule Modulators

E Pitsillou, JJ Liang, N Kino, JL Lockwood, A Hung… - …, 2024 - pmc.ncbi.nlm.nih.gov
Primary aldosteronism is characterised by the excessive production of aldosterone, which is
a key regulator of salt metabolism, and is the most common cause of secondary …

Identification of dietary compounds that interact with the circadian clock machinery: Molecular docking and structural similarity analysis

E Pitsillou, JJ Liang, RC Beh, A Hung… - Journal of Molecular …, 2023 - Elsevier
The molecular clock is vital for regulating circadian rhythms in various physiological
processes, and its dysregulation is associated with multiple diseases. As such, the use of …

[引用][C] Molecular Docking, Pharmacophore Modeling, 3D QSAR, Molecular Dynamics Simulation and MMPBSA Studies on Hydrazine-Linked Thiazole Analogues as …

C Zakiya Fathima, JP James, PSR Dwivedi… - Journal of …, 2024 - World Scientific
Background: Monoamine oxidase-B (MAO-B) is crucial in breaking down biogenic and
dietary amines, with its dysregulation linked to Parkinson's disease. Objective: This study …