RegulonDB, first published 20 years ago, is a comprehensive electronic resource about
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …

Metabolism is controlled to ensure organismal development and homeostasis. Several
mechanisms regulate metabolism, including allosteric control and transcriptional regulation …

Bacteria constantly monitor their environment to adapt their inner makeup. Beyond providing
chemical sustenance, metabolism provides most of the feedback on the cellular environment …

In free-living bacteria, the ability to regulate gene expression is at the core of adapting and
interacting with the environment. For these systems to have a logic, a signal must trigger a …

Background Norepinephrine (NE) signaling has a key role in white adipose tissue (WAT)
functions, including lipolysis, free fatty acid liberation and, under certain conditions …

In RegulonDB, for over 25 years, we have been gathering knowledge by manual curation
from original scientific literature on the regulation of transcription initiation and genome …

Transcription factors (TFs) are important drivers of cellular decision-making. When bacteria
encounter a change in the environment, TFs alter the expression of a defined set of genes in …

RegulonDB has collected, harmonized and centralized data from hundreds of experiments
for nearly two decades and is considered a point of reference for transcriptional regulation in …

The bacterial stress response is an intricately regulated system that plays a critical role in
cellular resistance to drug treatment. The complexity of this response is further complicated …

RegulonDB, first published 20 years ago, is a comprehensive electronic resource about
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …