Purpose This review provides an update on the current clinical, epidemiological and pathophysiological evidence alongside the diagnostic, prevention and treatment approach …
R Oun, YE Moussa, NJ Wheate - Dalton transactions, 2018 - pubs.rsc.org
The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose …
NP Staff, A Grisold, W Grisold… - Annals of …, 2017 - Wiley Online Library
Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting side effect experienced by patients receiving treatment for cancer. Approximately 30 to 40% of patients …
SJL Flatters, PM Dougherty… - BJA: British Journal of …, 2017 - academic.oup.com
This review provides an update on the current clinical and preclinical understanding of chemotherapy induced peripheral neuropathy (CIPN). The overview of the clinical syndrome …
With a 3‐fold increase in the number of cancer survivors noted since the 1970s, there are now over 28 million cancer survivors worldwide. Accordingly, there is a heightened …
NC Miltenburg, W Boogerd - Cancer treatment reviews, 2014 - Elsevier
Chemotherapy induced peripheral neuropathy (CIPN) is a potentially dose limiting side effect of commonly used chemotherapeutic agents like taxanes, vinca-alkaloids, platinum …
JR Brewer, G Morrison, ME Dolan, GF Fleming - Gynecologic oncology, 2016 - Elsevier
As there are increasing numbers of cancer survivors, more attention is being paid to the long term unwanted effects patients may experience as a result of their treatment and the impact …
The peripheral nervous system can be vulnerable to the toxic action of several drugs since it is not protected as effectively as the central nervous system from noxious exogenous agents …
PA Glare, PS Davies, E Finlay, A Gulati… - Journal of clinical …, 2014 - ascopubs.org
Pain is a common problem in cancer survivors, especially in the first few years after treatment. In the longer term, approximately 5% to 10% of survivors have chronic severe …