Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Abstract Phospholipases D (PLD) and C (PLC) hydrolyze the phosphodiesteric linkages of
the head group of membrane phospholipids. PLDs and PLCs in plants occur in different …

Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

▪ Abstract Eleven distinct isoforms of phosphoinositide-specific phospholipase C (PLC),
which are grouped into four subfamilies (β, γ, δ, and∍), have been identified in mammals …

Phosphoinositide-specific phospholipase C (PLC) subtypes β, γ, and δ comprise a related
group of multidomain phosphodiesterases that cleave the polar head groups from inositol …

Phosphoinositide-specific phospholipase C is an effector molecule in the signal transduction
process. It generates two second messengers, inositol-1, 4, 5-trisphosphate and …

Thromboxane A2 (TXA2), an unstable arachidonic acid metabolite, elicits diverse
physiological/pathophysiological actions, including platelet aggregation and smooth muscle …

The hydrolysis of a minor membrane phospholipid, phosphatidylinositol 4, 5-bisphosphate
(PIP2), 1 by a specific phospholipase C (PLC) is one of the earliest key events in the …

Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …

Tissue transglutaminase (TG) is a Ca2+-dependent acyltransferase with roles in cellular
differentiation, apoptosis, and other biological functions. In addition to being a transamidase …