“Vessels in the storm”: searching for prognostic and predictive angiogenic factors in colorectal cancer

A Angelucci, S Delle Monache, A Cortellini… - International journal of …, 2018 - mdpi.com
High expectations are placed upon anti-angiogenic compounds for metastatic colorectal
cancer (mCRC), the first malignancy for which such type of treatment has been approved …

HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer

EA Pudova, AV Kudryavtseva, MS Fedorova… - BMC genomics, 2018 - Springer
Background Colorectal cancer (CRC) is a common cancer worldwide. The main cause of
death in CRC includes tumor progression and metastasis. At molecular level, these …

Expression of HIF-1α and genes involved in glucose metabolism is increased in Cervical Cancer and HPV-16-Positive cell lines

VD Priego-Hernández, A Arizmendi-Izazaga… - Pathogens, 2022 - mdpi.com
Cervical cancer (CC) is the most common cancer in women in the lower genital tract. The
main risk factor for developing CC is persistent infection with HPV 16. The E6 and E7 …

COL1A1: A potential therapeutic target for colorectal cancer expressing wild-type or mutant KRAS

Z Zhang, C Fang, Y Wang, J Zhang… - International …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) treatment primarily relies on chemotherapy along with surgery,
radiotherapy and, more recently, targeted therapy at the late stages. However …

Expression patterns of microenvironmental factors and tenascin-C at the invasive front of stage II and III colorectal cancer: novel tumor prognostic markers

M Hashimoto, N Uesugi, M Osakabe… - Frontiers in …, 2021 - frontiersin.org
Background Biological markers expressed in cancer cells and the surrounding cancer-
associated fibroblasts (CAF) can be used for prediction of patient prognosis in colorectal …

PAICS is related to glioma grade and can promote glioma growth and migration

B Du, Z Zhang, W Di, W Xu, L Yang… - Journal of Cellular …, 2021 - Wiley Online Library
Glioma is a common malignant tumour of the brain. In this study, we aimed to investigate
diagnostic biomarkers and its role in glioma. Weighted gene co‐expression network …

[HTML][HTML] Apoptosis induction by siRNA targeting integrin-β1 and regorafenib/DDAB-mPEG-PCL hybrid nanoparticles in regorafenib-resistant colon cancer cells

M Zhiani, MA Mousavi, K Rostamizadeh… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is regarded as the third most common cancer worldwide. Although
Regorafenib as a receptor tyrosine kinase inhibitor (RTKI) disrupts tumor growth and …

[HTML][HTML] Changes in the Expression of Genes Regulating the Response to Hypoxia, Inflammation, Cell Cycle, Apoptosis, and Epithelial Barrier Functioning during …

D Dzhalilova, M Silina, I Tsvetkov, A Kosyreva… - International Journal of …, 2024 - mdpi.com
One of the factors contributing to colorectal cancer (CRC) development is inflammation,
which is mostly hypoxia-associated. This study aimed to characterize the morphological and …

Verbascoside attenuates Rac-1 and HIF-1α signaling cascade in colorectal cancer cells

D Seyfi, SB Behzad, M Nabiuni… - Anti-Cancer Agents …, 2018 - ingentaconnect.com
Objective: Metastasis phenotype is considered as the main challenge in colon cancer
therapeutic methods. Furthermore, the side effects of conventional colorectal cancer …

Bioinformatics Analysis Reveals E6 and E7 of HPV 16 Regulate Metabolic Reprogramming in Cervical Cancer, Head and Neck Cancer, and Colorectal Cancer …

A Arizmendi-Izazaga, N Navarro-Tito… - Current Issues in …, 2024 - mdpi.com
Human papillomavirus 16 (HPV 16) infection is associated with several types of cancer,
such as head and neck, cervical, anal, and penile cancer. Its oncogenic potential is due to …