Chronic inflammation and persistent oxidative stress contribute to the development and
progression of vascular proliferative diseases. We hypothesized that the proinflammatory …

Insulin resistance in the vasculature is a hallmark of type 2 diabetes (T2D), and blunting of
insulin-induced vasodilation is its primary consequence. Individuals with T2D exhibit a …

Keloids are characterized histologically by excessive fibroblast proliferation and connective
tissue deposition, and clinically by scar tissue extending beyond the original site of skin …

Atherosclerosis is a chronic inflammatory disease arising from an imbalance in lipid levels
and the accumulation of cholesterol-laden macrophages in the artery wall. Crocin is an …

Periodontitis is a chronic inflammatory oral disease that affects almost half of the adult
population. NF-κB activator 1 (Act1) is mainly expressed in immune cells, including …

Sustained inflammation and matrix metalloproteinase (MMP) activation contribute to
vascular occlusive/proliferative disorders. Interleukin‐17 (IL‐17) is a proinflammatory …

Insulin resistance in the vasculature is a characteristic feature of obesity and contributes to
the pathogenesis of vascular dysfunction and disease. However, the molecular mechanisms …

Atherosclerosis is a chronic inflammatory disease that poses a huge economic burden due
to its extremely poor prognosis. Therefore, it is necessary to explore potential mechanisms to …

Introduction Klotho protein is predominantly expressed in the kidneys and has also been
detected in vascular tissue and peripheral blood circulating cells to a lesser extent. Carotid …

This study aimed to explore the molecular mechanism of myocardial protection. The effects
of miR-32-3p and ring finger protein 13 (RNF13) on endoplasmic reticulum (ER) stress …