The cytostatic and apoptotic functions of transforming growth factor-β (TGF-β) help restrain
the growth of mammalian tissues; loss of these effects leads to hyperproliferative disorders …

Transforming growth factor β (TGF-β) superfamily signaling pathways are ubiquitous and
essential regulators of cellular processes including proliferation, differentiation, migration …

The transforming growth factor‐β (TGF‐β) signalling pathway plays a critical and dual role in
the progression of human cancer. During the early phase of tumour progression, TGF‐β acts …

Although the role of TGF-β in tumor progression has been studied extensively, its impact on
drug delivery in tumors remains far from understood. In this study, we examined the effect of …

Transforming growth factor-beta (TGF-β) is a multifunctional regulatory polypeptide that is
the prototypical member of a large family of cytokines that controls many aspects of cellular …

The transforming growth factor-ß (TGF-β) signaling pathway plays a pivotal role in diverse
cellular processes. TGF-β switches its role from a tumor suppressor in normal or dysplastic …

Introduction: The transforming growth factor-β (TGF-β) signaling pathway has a pivotal role
in tumor suppression and yet, paradoxically, in tumor promotion. Functional context …

Transforming growth factor-β (TGFβ) is a pleiotropic secretory cytokine exhibiting both
cancer-inhibitory and promoting properties. It transmits its signals via Suppressor of Mother …

Tumorigenesis is in many respects a process of dysregulated cellular evolution that drives
malignant cells to acquire six phenotypic hallmarks of cancer, including their ability to …

The transforming growth factor-beta (TGF-!) belongs to a superfamily of cytokines that act on
protein kinase receptors at the plasma membrane to induce a plethora of biological signals …