During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

Brain systems that promote the maintenance of homeostasis in face of stress have
significant adaptive value. A growing body of work across species demonstrates a critical …

Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

Major depressive disorder (MDD) is a psychiatric disorder with increasing prevalence
worldwide. It is a leading cause of disability and suicide, severely affecting physical and …

Ever since their discoveries, the Wnt pathways have been consistently associated with key
features of cellular development, including metabolism, structure and cell fate. The three …

Background We aim to identify the molecular mechanisms for curcumin's anti-depressant
properties, including genes, transcription factors, and miRNAs. Methods The Comparative …

Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …

Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …

Mood disorders are the most prevalent psychiatric disorders associated with significant
disability, morbidity, and mortality. The risk of suicide is associated with severe or mixed …

Depression is a psychiatric disorder that presents with a persistent depressed mood as the
main clinical feature and is accompanied by cognitive impairment. Changes in …