Aurora is the name given to a family of highly conserved protein kinases with essential roles
in many aspects of cell division. Yeasts have a single Aurora kinase, whereas mammals …

Mitosis and meiosis are remarkable processes during which cells undergo profound
changes in their structure and physiology. These events are orchestrated with a precision …

Ceulemans, Hugo, and Mathieu Bollen. Functional Diversity of Protein Phosphatase-1, a
Cellular Economizer and Reset Button. Physiol Rev 84: 1–39, 2004; 10.1152/physrev …

The three human homologues of Aurora kinases (A, B and C) are essential for proper
execution of various mitotic events and are important for maintaining genomic integrity …

The synaptonemal complex (SC) is a meiosis-specific scaffold that links homologous
chromosomes from end to end during meiotic prophase and is required for the formation of …

Eukaryotic cells must possess mechanisms for condensing and decondensing chromatin.
Chromatin condensation is particularly evident during mitosis and cell death induced by …

Aurora kinase belongs to serine/threonine kinase family which controls cell division.
Therapeutic inhibition of Aurora kinase showed great promise as probable anticancer …

During cell division, each daughter cell inherits one copy of every chromosome. Accurate
transmission of chromosomes requires that the sister DNA molecules created during DNA …

Cohesin is an evolutionary conserved multi‐protein complex that plays a pivotal role in
chromosome dynamics. It plays a role both in sister chromatid cohesion and in establishing …

The establishment of metaphase chromosomes is an essential prerequisite of sister
chromatid separation in anaphase. It involves the coordinated action of cohesin and …