Molecular and supramolecular structure of the mitochondrial oxidative phosphorylation system: implications for pathology

S Nesci, F Trombetti, A Pagliarani, V Ventrella… - Life, 2021 - mdpi.com
Under aerobic conditions, mitochondrial oxidative phosphorylation (OXPHOS) converts the
energy released by nutrient oxidation into ATP, the currency of living organisms. The whole …

Regulation of inflammation and oxidative stress by formyl peptide receptors in cardiovascular disease progression

VM Caso, V Manzo, T Pecchillo Cimmino, V Conti… - Life, 2021 - mdpi.com
G protein-coupled receptors (GPCRs) are the most important regulators of cardiac function
and are commonly targeted for medical therapeutics. Formyl-Peptide Receptors (FPRs) are …

[HTML][HTML] Physiological responses of contrasting rice genotypes to salt stress at reproductive stage

MEB Gerona, MP Deocampo, JA Egdane, AM Ismail… - Rice Science, 2019 - Elsevier
Salinity is a major abiotic stress affecting plant growth and productivity. Considerable
genetic variation is present in rice in response to salt stress, with higher sensitivity during …

Alkaline taste sensation through the alkaliphile chloride channel in Drosophila

T Mi, JO Mack, W Koolmees, Q Lyon… - Nature …, 2023 - nature.com
The sense of taste is an important sentinel governing what should or should not be ingested
by an animal, with high pH sensation playing a critical role in food selection. Here we …

tRNA methylation is a global determinant of bacterial multi-drug resistance

I Masuda, R Matsubara, T Christian, ER Rojas… - Cell systems, 2019 - cell.com
Gram-negative bacteria are intrinsically resistant to drugs because of their double-
membrane envelope structure that acts as a permeability barrier and as an anchor for efflux …

[HTML][HTML] Dual-function peptides derived from egg white ovalbumin: Bioinformatics identification with validation using in vitro assay

MASM Salim, CY Gan - Journal of functional foods, 2020 - Elsevier
A complete integrated bioinformatics approach was developed to identify angiotensin-
converting enzyme (ACE) and dipeptidyl peptidase-4 (DPP-4) inhibitory peptides from egg …

Subnanometer resolution cryo-EM structure of Arabidopsis thaliana ATG9

LTF Lai, C Yu, JSK Wong, HS Lo, S Benlekbir, L Jiang… - Autophagy, 2020 - Taylor & Francis
Macroautophagy/autophagy is an essential process for the maintenance of cellular
homeostasis by recycling macromolecules under normal and stress conditions. ATG9 …

Properties of peptides released from salmon and carp via simulated human-like gastrointestinal digestion described applying quantitative parameters

J Borawska-Dziadkiewicz, M Darewicz… - PLoS One, 2021 - journals.plos.org
Apart from the classical (experimental) methods, biologically active peptides can be studied
via bioinformatics approach, also known as in silico analysis. This study aimed to verify the …

Mitochondrial F-type ATP synthase: multiple enzyme functions revealed by the membrane-embedded FO structure

S Nesci, A Pagliarani, C Algieri… - Critical reviews in …, 2020 - Taylor & Francis
Of the two main sectors of the F-type ATP synthase, the membrane-intrinsic FO domain is the
one which, during evolution, has undergone the highest structural variations and changes in …

[HTML][HTML] Deep metabolic phenotyping of humans with protein-altering variants in TM6SF2 using a genome-first approach

HYR Huang, C Vitali, D Zhang, NJ Hand, MC Phillips… - JHEP Reports, 2025 - Elsevier
Background & Aim An unbiased genome-first approach can expand the molecular
understanding of specific genes in disease-agnostic biobanks for deeper phenotyping …