Epidemiology and pathophysiology of multiple sclerosis

M Ward, MD Goldman - CONTINUUM: Lifelong Learning in …, 2022 - journals.lww.com
Epidemiology and Pathophysiology of Multiple Sclerosis : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …

Impact of metabolic syndrome on neuroinflammation and the blood–brain barrier

P Van Dyken, B Lacoste - Frontiers in neuroscience, 2018 - frontiersin.org
Metabolic syndrome, which includes diabetes and obesity, is one of the most widespread
medical conditions. It induces systemic inflammation, causing far reaching effects on the …

Comorbidity in multiple sclerosis

M Magyari, PS Sorensen - Frontiers in Neurology, 2020 - frontiersin.org
Comorbidities in patients with multiple sclerosis (MS) has become an area of increasing
interest in the recent years. A comorbidity is defined as any additional disease that coexists …

Treatment optimization in multiple sclerosis: Canadian MS working group recommendations

MS Freedman, V Devonshire, P Duquette… - Canadian Journal of …, 2020 - cambridge.org
The Canadian Multiple Sclerosis Working Group has updated its treatment optimization
recommendations (TORs) on the optimal use of disease-modifying therapies for patients …

The potential therapeutic effect of statins in multiple sclerosis: beneficial or detrimental effects

HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Multiple sclerosis (MS) is a chronic progressive disabling disease of the central nervous
system (CNS) characterized by demyelination and neuronal injury. Dyslipidemia is observed …

The topographical model of multiple sclerosis: a dynamic visualization of disease course

SC Krieger, K Cook, S De Nino… - Neurology …, 2016 - AAN Enterprises
Relapses and progression contribute to multiple sclerosis (MS) disease course, but neither
the relationship between them nor the spectrum of clinical heterogeneity has been fully …

Comorbidity increases the risk of relapse in multiple sclerosis: a prospective study

K Kowalec, KA McKay, SB Patten, JD Fisk, C Evans… - Neurology, 2017 - AAN Enterprises
Objective: To evaluate the association between comorbidity and relapse rate in individuals
with multiple sclerosis (MS). Methods: We recruited individuals with prevalent relapsing …

Hypertension and heart disease are associated with development of brain atrophy in multiple sclerosis: a 5‐year longitudinal study

D Jakimovski, S Gandhi, I Paunkoski… - European journal of …, 2019 - Wiley Online Library
Background Cardiovascular diseases (CVD s) are more frequent in multiple sclerosis (MS)
patients when compared to controls. In particular, CVD s are linked with higher accumulation …

The prevalence of diabetes mellitus type II (DMII) in the multiple sclerosis population: a systematic review and meta-analysis

V Giannopapas, L Palaiodimou, D Kitsos… - Journal of Clinical …, 2023 - mdpi.com
Introduction: The interactions between Diabetes Mellitus type II (DMII) and Multiple Sclerosis
(MS) lead to higher levels of fatigue, higher risk of physical disability, faster cognitive …

Understanding a role for hypoxia in lesion formation and location in the deep and periventricular white matter in small vessel disease and multiple sclerosis

S Martinez Sosa, KJ Smith - Clinical Science, 2017 - portlandpress.com
The deep and periventricular white matter is preferentially affected in several neurological
disorders, including cerebral small vessel disease (SVD) and multiple sclerosis (MS) …