Duchenne muscular dystrophy (DMD) is an X-linked hereditary disease characterized by
progressive muscle wasting due to modifications in the DMD gene (exon deletions …

Whilst a disease-modifying treatment for Facioscapulohumeral muscular dystrophy (FSHD)
does not exist currently, recent advances in complex molecular pathophysiology studies of …

Sporadic inclusion body myositis (IBM) is the most common acquired muscle disease in
adults over age 50, yet it remains unclear whether the disease is primarily driven by T cell …

Duchenne muscular dystrophy is a highly progressive muscle wasting disorder due to
primary abnormalities in one of the largest genes in the human genome, the DMD gene …

Aging is a one-way process associated with profound structural and functional changes in
the organism. Indeed, the neuromuscular system undergoes a wide remodeling, which …

Skeletal muscle accounts for almost 40% of the total adult human body mass. This tissue is
essential for structural and mechanical functions such as posture, locomotion, and …

Facioscapulohumeral muscular dystrophy (FSHD) is a common muscle dystrophy typically
affecting patients within their second decade. Patients initially exhibit asymmetric facial and …

Xenografts of human skeletal muscle generated in mice can be used to study muscle
pathology and to test drugs designed to treat myopathies and muscular dystrophies for their …

Cells with contractile functions are present in almost all metazoans, and so are the related
processes of muscle homeostasis and regeneration. Regeneration itself is a complex …

Gene therapy involves replacing a faulty gene or adding a new gene inside the body's cells
to cure disease or improve the body's ability to fight disease. Its popularity is evident from …