Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals
In recent years, great progress has been made in the field of new therapeutic options for
hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a …
hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a …
A single nucleotide polymorphism, rs129679860, in the IL28B locus is associated with the viral kinetics and a sustained virological response in a chronic …
JA Ramos, ALA Ramos, L Hoffmann… - Memórias do Instituto …, 2012 - SciELO Brasil
Single nucleotide polymorphisms (SNPs) in the interleukin (IL) 28B locus have been
associated with a sustained virological response (SVR) in interferon-ribavirin (IFN-RBV) …
associated with a sustained virological response (SVR) in interferon-ribavirin (IFN-RBV) …
Association of cytokine gene polymorphisms with hepatitis C virus infection in a population from Rio de Janeiro, Brazil
GM Fabrício-Silva, BS Poschetzky… - Hepatic medicine …, 2015 - Taylor & Francis
Background The host immune response is an important indicator of the outcome of hepatitis
C virus (HCV) infection and disease progression. The aim of this study was to explore …
C virus (HCV) infection and disease progression. The aim of this study was to explore …
The role of pharmacogenetics in the treatment of chronic hepatitis C infection
M Kawaguchi‐Suzuki, RF Frye - Pharmacotherapy: The Journal …, 2014 - Wiley Online Library
Hepatitis C virus (HCV) chronically infects 170 million people worldwide. Until recently,
combination therapy with peginterferon‐α (peg IFN) and ribavirin (RBV) has been the …
combination therapy with peginterferon‐α (peg IFN) and ribavirin (RBV) has been the …
Differences in virological response to peginterferon-α plus ribavirin in HIV-positive patients coinfected with HCV subtypes 1a or 1b
Background: Both viral and host factors influence response to peginterferon-α plus ribavirin
(pegIFNα/RBV) in patients with chronic hepatitis C. The impact of these variables is more …
(pegIFNα/RBV) in patients with chronic hepatitis C. The impact of these variables is more …
CCR5-∆ 32, CCR2-64I, SDF1-3'A, and IFNλ4 rs12979860 and rs8099917 gene polymorphisms in individuals with HIV-1, HIV/HTLV-1, and HIV/HTLV-2 in São Paulo …
A Caterino-de-Araujo, KR Campos… - Microbes, Infection …, 2023 - revistas.unheval.edu.pe
Background. Chemokine and chemokine-receptor polymorphisms have been associated
with protection against HIV infection and delayed progression to AIDS, whereas …
with protection against HIV infection and delayed progression to AIDS, whereas …
IL28B Polymorphisms Among Latin American HCV Patients
A Soza, M Lopez-Lastra - Current Hepatitis Reports, 2013 - Springer
Latin America is a diverse region with more than 500 million people and approximately 8
million HCV infected individuals. The recent description of genetic polymorphisms …
million HCV infected individuals. The recent description of genetic polymorphisms …
Saúde pública
AMS Silva - Revista Portuguesa de Medicina Geral e Familiar, 2007 - rpmgf.pt
406 Rev Port Clin Geral 2007; 23: 405-7 miológicos disponíveis), sublinhando os critérios
de qualidade, eficácia e segurança das vacinas e ainda as exigências técnicas e logísticas …
de qualidade, eficácia e segurança das vacinas e ainda as exigências técnicas e logísticas …
Associação dos polimorfismos de IFN-lambda 4, KIR e HLA-C em pacientes vivendo com HTLV-1
TA Santos - 2016 - teses.usp.br
As doenças virais têm sido importantes causas de morbidade e mortalidade nas últimas
décadas, sendo que algumas delas são relacionadas com polimorfismos genéticos, que …
décadas, sendo que algumas delas são relacionadas com polimorfismos genéticos, que …
Determinação do perfil do polimorfismo da IL28B em indivíduos coinfectados pelo vírus da Hepatite C Crônica (HCV) e pelo vírus linfotrópico de células T humanas …
TA Santos - 2013 - teses.usp.br
O polimorfismo de IL28B foi descrito como fator importante na patogênese de infecções
causadas por alguns vírus. O objetivo desta pesquisa foi avaliar se polimorfismos (SNP …
causadas por alguns vírus. O objetivo desta pesquisa foi avaliar se polimorfismos (SNP …