Conceptualizing mental disorders as deviations from normative functioning
Normative models are a class of emerging statistical techniques useful for understanding the
heterogeneous biology underlying psychiatric disorders at the level of the individual …
heterogeneous biology underlying psychiatric disorders at the level of the individual …
The normative modeling framework for computational psychiatry
Normative modeling is an emerging and innovative framework for mapping individual
differences at the level of a single subject or observation in relation to a reference model. It …
differences at the level of a single subject or observation in relation to a reference model. It …
Aerobic exercise alters brain function and structure in Parkinson's disease: a randomized controlled trial
ME Johansson, IGM Cameron… - Annals of …, 2022 - Wiley Online Library
Objective Randomized clinical trials have shown that aerobic exercise attenuates motor
symptom progression in Parkinson's disease, but the underlying neural mechanisms are …
symptom progression in Parkinson's disease, but the underlying neural mechanisms are …
Evidence for embracing normative modeling
In this work, we expand the normative model repository introduced in Rutherford et al.,
2022a to include normative models charting lifespan trajectories of structural surface area …
2022a to include normative models charting lifespan trajectories of structural surface area …
Mapping the heterogeneous phenotype of schizophrenia and bipolar disorder using normative models
Importance Schizophrenia and bipolar disorder are severe and complex brain disorders
characterized by substantial clinical and biological heterogeneity. However, case-control …
characterized by substantial clinical and biological heterogeneity. However, case-control …
Identification of psychiatric disorder subtypes from functional connectivity patterns in resting-state electroencephalography
The understanding and treatment of psychiatric disorders, which are known to be
neurobiologically and clinically heterogeneous, could benefit from the data-driven …
neurobiologically and clinically heterogeneous, could benefit from the data-driven …
[HTML][HTML] NeuroMark: An automated and adaptive ICA based pipeline to identify reproducible fMRI markers of brain disorders
Many mental illnesses share overlapping or similar clinical symptoms, confounding the
diagnosis. It is important to systematically characterize the degree to which unique and …
diagnosis. It is important to systematically characterize the degree to which unique and …
Using two-step cluster analysis and latent class cluster analysis to classify the cognitive heterogeneity of cross-diagnostic psychiatric inpatients
M Benassi, S Garofalo, F Ambrosini… - Frontiers in …, 2020 - frontiersin.org
The heterogeneity of cognitive profiles among psychiatric patients has been reported to
carry significant clinical information. However, how to best characterize such cognitive …
carry significant clinical information. However, how to best characterize such cognitive …
The WPA-lancet psychiatry commission on the future of psychiatry
Background This Commission addresses several priority areas for psychiatry over the next
decade, and into the 21st century. These represent challenges and opportunities for the …
decade, and into the 21st century. These represent challenges and opportunities for the …
[HTML][HTML] Classification and prediction of brain disorders using functional connectivity: promising but challenging
Brain functional imaging data, especially functional magnetic resonance imaging (fMRI)
data, have been employed to reflect functional integration of the brain. Alteration in brain …
data, have been employed to reflect functional integration of the brain. Alteration in brain …