Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐and aging‐related diseases

AG Panossian, T Efferth, AN Shikov… - Medicinal research …, 2021 - Wiley Online Library
Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

Plant adaptogens—History and future perspectives

V Todorova, K Ivanov, C Delattre, V Nalbantova… - Nutrients, 2021 - mdpi.com
Adaptogens are synthetic compounds (bromantane, levamisole, aphobazole, bemethyl, etc.)
or plant extracts that have the ability to enhance the body's stability against physical loads …

Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy

A Panossian, G Wikman, J Sarris - Phytomedicine, 2010 - Elsevier
The aim of this review article was to summarize accumulated information related to chemical
composition, pharmacological activity, traditional and official use of Rhodiola rosea L. in …

Простые лекарственные средства

ИД Кароматов - 2012 - elibrary.ru
Монография попытка автора воссоединить воедино данные народной, традиционной
и научной медицины по применению лекарственных средств натурального …

[PDF][PDF] Chronic stress and the HPA axis

TG Guilliams, L Edwards - The standard, 2010 - pointinstitute.org
Humans have been designed with a complex repertoire of metabolic machinery intended to
maintain normal homeostasis. This physiologic state of balance is susceptible to various …

Understanding adaptogenic activity: specificity of the pharmacological action of adaptogens and other phytochemicals

A Panossian - Annals of the New York Academy of Sciences, 2017 - Wiley Online Library
Adaptogens are stress‐response modifiers that increase an organism's nonspecific
resistance to stress by increasing its ability to adapt and survive. The classical reductionist …

A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide

L Liao, Y He, L Li, H Meng, Y Dong, F Yi, P Xiao - Chinese medicine, 2018 - Springer
Modern studies have shown that adaptogens can non-specifically enhance the resistance of
human body under a wide range of external stress conditions with a multi-targeted and multi …

[HTML][HTML] Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress—protective activity

A Panossian, G Wikman - Pharmaceuticals, 2010 - mdpi.com
Adaptogens were initially defined as substances that enhance the “state of non-specific
resistance” in stress, a physiological condition that is linked with various disorders of the …

Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study

H Tao, X Wu, J Cao, Y Peng, A Wang… - Medicinal Research …, 2019 - Wiley Online Library
Rhodiola species, belonging to the family Crassulaceae, have long been used as an
adaptogen, tonic, antidepressant, and antistress medicine or functional food in Asia and …

Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity

A Panossian, G Wikman - Current clinical pharmacology, 2009 - ingentaconnect.com
The aim of this review article is to assess the level of scientific evidence presented by clinical
trials of adaptogens in fatigue, and to provide a rationale at the molecular level for verified …