The variant gambit: COVID-19's next move

JA Plante, BM Mitchell, KS Plante, K Debbink… - Cell host & …, 2021 - cell.com
More than a year after its emergence, COVID-19, the disease caused by SARS-CoV-2,
continues to plague the world and dominate our daily lives. Even with the development of …

[HTML][HTML] Genetics and genomics of SARS-CoV-2: A review of the literature with the special focus on genetic diversity and SARS-CoV-2 genome detection

A Rahimi, A Mirzazadeh, S Tavakolpour - Genomics, 2021 - Elsevier
The outbreak of 2019-novel coronavirus disease (COVID-19), caused by SARS-CoV-2,
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …

Evolution of SARS-CoV-2: review of mutations, role of the host immune system

H Banoun - Nephron, 2021 - karger.com
Since the reporting of the first cases of coronavirus in China and the publication of the first
sequence of SARS-CoV-2 in December 2019, the virus has undergone numerous …

Emerging SARS-CoV-2 variants: a review of its mutations, its implications and vaccine efficacy

S Ramesh, M Govindarajulu, RS Parise, L Neel… - Vaccines, 2021 - mdpi.com
The widespread increase in multiple severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) variants is causing a significant health concern in the United States and …

UMAP-assisted K-means clustering of large-scale SARS-CoV-2 mutation datasets

Y Hozumi, R Wang, C Yin, GW Wei - Computers in biology and medicine, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has a worldwide devastating effect. Understanding …

Global analysis of more than 50,000 SARS-CoV-2 genomes reveals epistasis between eight viral genes

HL Zeng, V Dichio, E Rodríguez Horta… - Proceedings of the …, 2020 - National Acad Sciences
Genome-wide epistasis analysis is a powerful tool to infer gene interactions, which can
guide drug and vaccine development and lead to deeper understanding of microbial …

SARS-CoV-2 genomic characterization and clinical manifestation of the COVID-19 outbreak in Uruguay

V Elizondo, GW Harkins, B Mabvakure… - Emerging microbes & …, 2021 - Taylor & Francis
ABSTRACT COVID-19 is a respiratory illness caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and declared by the World Health Organization a global public …

Molecular epidemiology surveillance of SARS-CoV-2: mutations and genetic diversity one year after emerging

A Flores-Alanis, A Cruz-Rangel, F Rodríguez-Gómez… - Pathogens, 2021 - mdpi.com
In December 2019, the first cases of the novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) were identified in the city of Wuhan, China. Since then, it has …

Decoding Covid-19 with the SARS-CoV-2 genome

P Ellis, F Somogyvári, DP Virok, M Noseda… - … genetic medicine reports, 2021 - Springer
Abstract Purpose of Review SARS-CoV-2, the recently emerged coronavirus (CoV) that is
responsible for the current global pandemic Covid-19, first appeared in late 2019 in Wuhan …

SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

RN Tasakis, G Samaras, A Jamison, M Lee, A Paulus… - PLoS …, 2021 - journals.plos.org
Since the first case of COVID-19 in December 2019 in Wuhan, China, SARS-CoV-2 has
spread worldwide and within a year and a half has caused 3.56 million deaths globally. With …