Radiosyntheses using fluorine-18: the art and science of late stage fluorination
EL Cole, MN Stewart, R Littich… - Current topics in …, 2014 - ingentaconnect.com
Positron (β+) emission tomography (PET) is a powerful, noninvasive tool for the in vivo, three-
dimensional imaging of physiological structures and biochemical pathways. The continued …
dimensional imaging of physiological structures and biochemical pathways. The continued …
18F-Labeled Peptides: The Future Is Bright
S Richter, F Wuest - Molecules, 2014 - mdpi.com
Radiolabeled peptides have been the subject of intense research efforts for targeted
diagnostic imaging and radiotherapy over the last 20 years. Peptides offer several …
diagnostic imaging and radiotherapy over the last 20 years. Peptides offer several …
[18 F]-Group 13 fluoride derivatives as radiotracers for positron emission tomography
The field of 18F chemistry is rapidly expanding because of the use of this radionuclide in
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …
[HTML][HTML] Lewis acid-assisted isotopic 18F-19F exchange in BODIPY dyes: facile generation of positron emission tomography/fluorescence dual modality agents for …
S Liu, TP Lin, D Li, L Leamer, H Shan, Z Li… - Theranostics, 2013 - ncbi.nlm.nih.gov
Positron emission tomography (PET) is a powerful technique for imaging biological
pathways in vivo, particularly those that are key targets in disease processes. In contrast …
pathways in vivo, particularly those that are key targets in disease processes. In contrast …
Anion capture and sensing with cationic boranes: on the synergy of Coulombic effects and onium ion-centred Lewis acidity
Stimulated by the growing importance and recognized toxicity of anions such as fluoride,
cyanide and azides, we have, in the past few years, developed a family of Lewis acidic …
cyanide and azides, we have, in the past few years, developed a family of Lewis acidic …
One-step 18F labeling of biomolecules using organotrifluoroborates
Herein we present a general protocol for the functionalization of biomolecules with an
organotrifluoroborate moiety so that they can be radiolabeled with aqueous 18F fluoride …
organotrifluoroborate moiety so that they can be radiolabeled with aqueous 18F fluoride …
From Unorthodox to Established: The Current Status of 18F-Trifluoroborate- and 18F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging
V Bernard-Gauthier, JJ Bailey, Z Liu… - Bioconjugate …, 2016 - ACS Publications
Unorthodox 18F-labeling strategies not employing the formation of a carbon-18F bond are
seldom found in radiochemistry. Historically, the formation of a boron-or silicon-18F bond …
seldom found in radiochemistry. Historically, the formation of a boron-or silicon-18F bond …
Reaction of [18F]Fluoride at Heteroatoms and Metals for Imaging of Peptides and Proteins by Positron Emission Tomography
The ability to radiolabel proteins with [18F] fluoride enables the use of positron emission
tomography (PET) for the early detection, staging and diagnosis of disease. The direct …
tomography (PET) for the early detection, staging and diagnosis of disease. The direct …
Sulfonyl Fluoride‐Based Prosthetic Compounds as Potential 18F Labelling Agents
JAH Inkster, K Liu, S Ait‐Mohand… - … A European Journal, 2012 - Wiley Online Library
Nucleophilic incorporation of [18F] F− under aqueous conditions holds several advantages
in radiopharmaceutical development, especially with the advent of complex biological …
in radiopharmaceutical development, especially with the advent of complex biological …
Fluorescent kinase inhibitors as probes in cancer
Fluorescent dyes attached to kinase inhibitors (KIs) can be used to probe kinases in vitro, in
cells, and in vivo. Ideal characteristics of the dyes vary with their intended applications …
cells, and in vivo. Ideal characteristics of the dyes vary with their intended applications …