Colorectal cancer (CRC) is the world's third most prevalent cancer and the main cause of
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …

Colorectal cancer (CRC) is a leading cause of death among cancer patients. This
heterogeneous disease is characterized by alterations in multiple molecular pathways …

Background The interim analysis of the multicentre New EPOC trial in patients with
resectable colorectal liver metastasis showed a significant reduction in progression-free …

Colorectal cancer (CRC) remains a serious health problem worldwide. Approximately half of
patients will develop distant metastasis after CRC resection, usually with very poor …

Epigenetic alterations play a key role in the initiation and progression of cancer. Therefore, it
is possible to use epigenetic marks as biomarkers for predictive and precision medicine in …

Alterations in the transcriptional factor c-MYC could be involved in the anti-EGFR resistance
in metastatic colorectal cancer (mCRC). The c-MYC expression was evaluated in 121 RAS …

The approval of targeted therapies for metastatic colorectal cancer (mCRC) has led to
important improvements in patient outcomes. However, it is still necessary to increase …

YKL-40 is a heparin-and chitin-binding glycoprotein that belongs to the family of glycosyl
hydrolases but lacks enzymatic properties. It affects different (patho) physiological …

Over the past years, colorectal cancer (CRC) was subtyped according to its molecular and
genetic characteristics, allowing the development of therapeutic strategies, based on …

AIM To explore the expression of microRNA miR-19a-3p and Forkhead box F2 (FOXF2) in
patients with CRC and the relevant mechanisms. METHODS Sixty-two CRC patients …