Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

IJ Neeland, R Ross, JP Després… - The lancet Diabetes & …, 2019 - thelancet.com
Findings from epidemiological studies over the past 30 years have shown that visceral
adipose tissue, accurately measured by CT or MRI, is an independent risk marker of …

Nonalcoholic fatty liver disease 2020: the state of the disease

TG Cotter, M Rinella - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …

The effect of the Mediterranean diet on metabolic health: a systematic review and meta-analysis of controlled trials in adults

A Papadaki, E Nolen-Doerr, CS Mantzoros - Nutrients, 2020 - mdpi.com
The Mediterranean diet (MD) may provide metabolic benefits but no systematic review to
date has examined its effect on a multitude of outcomes related to metabolic health. This …

[HTML][HTML] Metabolic syndrome: risk factors, diagnosis, pathogenesis, and management with natural approaches

SM Mohamed, MA Shalaby, RA El-Shiekh… - Food Chemistry …, 2023 - Elsevier
Metabolic syndrome (MetS) is a bunch of metabolic defects comprising hypertension, insulin
resistance, visceral obesity, fatty liver, and atherogenic cardiovascular diseases. Lifestyle …

Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids

R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido… - Cell metabolism, 2019 - cell.com
Human organoid systems recapitulate in vivo organ architecture yet fail to capture complex
pathologies such as inflammation and fibrosis. Here, using 11 different healthy and …

Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology

M Eslam, J George - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
Nonalcoholic fatty liver disease (NAFLD) affects around a quarter of the global population,
paralleling worldwide increases in obesity and metabolic syndrome. NAFLD arises in the …

Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review

L Rinaldi, PC Pafundi, R Galiero, A Caturano… - Antioxidants, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …

Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review

EP Stahl, DS Dhindsa, SK Lee, PB Sandesara… - Journal of the American …, 2019 - jacc.org
Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) are both
manifestations of end-organ damage of the metabolic syndrome. Through multiple …

[PDF][PDF] Fibrosis stage is the strongest predictor for disease‐specific mortality in NAFLD after up to 33 years of follow‐up

M Ekstedt, H Hagström, P Nasr, M Fredrikson… - …, 2015 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the Western
world, strongly associated with insulin resistance and the metabolic syndrome. Nonalcoholic …

Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications

SM Francque, D Van Der Graaff, WJ Kwanten - Journal of hepatology, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has become one of the most frequent chronic liver
diseases in the Western society and its prevalence is likely to rise even further. An …