GDF15 has recently gained scientific and translational prominence with the discovery that its
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain …

Within the past several decades, the emergence of new viral diseases with severe health
complications and mortality is evidence of an age-dependent, compromised bodily response …

Abstract Growth differentiation factor 15 (GDF15) is a peptide hormone, and a divergent
member of the transforming growth factor beta (TGFβ) superfamily. In normal physiology …

Determination of specific cardiac biomarkers (CBs) during the diagnosis and management
of adverse cardiovascular events such as acute myocardial infarction (AMI) has become …

Abstract Growth differentiation factor 15 (GDF15), a member of the transforming growth
factor-beta superfamily, is expressed in several human organs. In particular, it is highly …

Background Heterogeneity of acute respiratory distress syndrome (ARDS) could be reduced
by identification of biomarker-based phenotypes. The set of ARDS biomarkers to …

Rationale The molecular mechanisms underlying the muscle atrophy of intensive care unit-
acquired weakness (ICUAW) are poorly understood. We hypothesised that increased …

Acute respiratory distress syndrome (ARDS) is defined as an acute-onset, progressive,
hypoxic condition with radiographic bilateral lung infiltration, which develops after several …

Growth differentiation factor‐15 (GDF‐15) is a member of the transforming growth factor‐β
superfamily related to inflammation and macrophage activation. Serum concentrations of …

Growth Differentiation Factor 15 (GDF15) is a divergent member of transforming growth
factor-beta (TGF-β) superfamily and is ubiquitously expressed, under normal physiological …