Patients with established type 2 diabetes display both β-cell dysfunction and insulin
resistance. To define fundamental processes leading to the diabetic state, we examined the …

Clustering is the unsupervised, semisupervised, and supervised classification of patterns
into groups. The clustering problem has been addressed in many contexts and disciplines …

Abstract Background Non-pharmaceutical interventions (NPIs) are used to reduce
transmission of SARS coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 …

INTRODUCTION The brains of extant animals have evolved over hundreds of millions of
years from simple circuits. Cell types diversified, connections elaborated, and new brain …

Numerical Ecology with R provides a long-awaited bridge between a textbook in Numerical
Ecology and the implementation of this discipline in the R language. After short theoretical …

The idea for this book came from the time the authors spent at the Statistics and Applied
Mathematical Sciences Institute (SAMSI) in Research Triangle Park in North Carolina …

Aim The oceans harbour a great diversity of organisms whose distribution and ecological
preferences are often poorly understood. Species distribution modelling (SDM) could …

Abstract Development of a highly reproducible and sensitive single-cell RNA sequencing
(RNA-seq) method would facilitate the understanding of the biological roles and underlying …

Pvclust is an add-on package for a statistical software R to assess the uncertainty in
hierarchical cluster analysis. Pvclust can be used easily for general statistical problems …

Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes
genome architecture and is often assumed to be causally associated with organismal …