Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …

Skeletal muscle-specific stem cells are pivotal for tissue development and regeneration.
Muscle plasticity, inherent in these processes, is also essential for daily life activities. Great …

Maintenance of the highly organized striated muscle tissue requires a cell-wide dynamic
network that through interactions with all vital cell structures, provides an effective …

Intermediate filament (IF) proteins are critical regulators in health and disease. The
discovery of hundreds of mutations in IF genes and posttranslational modifications has been …

Desmin is a muscle-specific type III intermediate filament essential for proper muscular
structure and function. In human, mutations affecting desmin expression or promoting its …

Type III intermediate filament (IF) proteins assemble into cytoplasmic homopolymeric and
heteropolymeric filaments with other type III and some type IV IFs. These highly dynamic …

Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A
multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with …

The remarkable adaptive and regenerative capacity of skeletal muscle is regulated by
several transcription factors and pathways. Here we show that the transcription factor Prox1 …

DNA methylation, which is modulated by both genetic factors and environmental exposures,
may offer a unique opportunity to discover novel biomarkers of disease-related brain …