Analysis of DNA methylation in cancer: location revisited

A Koch, SC Joosten, Z Feng, TC de Ruijter… - Nature reviews Clinical …, 2018 - nature.com
Abstract Changes in DNA methylation in cancer have been heralded as promising targets
for the development of powerful diagnostic, prognostic, and predictive biomarkers. Despite …

DNA methylation profiles in cancer diagnosis and therapeutics

Y Pan, G Liu, F Zhou, B Su, Y Li - Clinical and experimental medicine, 2018 - Springer
Cancer initiation and proliferation is regulated by both epigenetic and genetic events with
epigenetic modifications being increasingly identified as important targets for cancer …

Epidemiology of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines

AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - Elsevier
Background Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …

[HTML][HTML] Mechanisms and metabolic implications of regional differences among fat depots

T Tchkonia, T Thomou, YI Zhu, I Karagiannides… - Cell metabolism, 2013 - cell.com
Fat distribution is closely linked to metabolic disease risk. Distribution varies with sex,
genetic background, disease state, certain drugs and hormones, development, and aging …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

DNA methylation biomarkers: cancer and beyond

T Mikeska, JM Craig - Genes, 2014 - mdpi.com
Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Early detection of lung cancer biomarkers through biosensor technology: A review

A Roointan, TA Mir, SI Wani, KK Hussain… - … of pharmaceutical and …, 2019 - Elsevier
Lung cancer is undoubtedly one of the most serious health issues of the 21 st century. It is
the second leading cause of cancer-related deaths in both men and women worldwide …

The role of liquid biopsy in early diagnosis of lung cancer

C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …

Lung cancer in patients with idiopathic pulmonary fibrosis

T Karampitsakos, V Tzilas, R Tringidou… - Pulmonary …, 2017 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease of unknown etiology.
With a gradually increasing worldwide prevalence and a mortality rate exceeding that of …

Point-of-care cancer diagnostic devices: From academic research to clinical translation

L Syedmoradi, ML Norton, K Omidfar - Talanta, 2021 - Elsevier
Early and timely diagnosis of cancer plays a decisive role in appropriate treatment and
improves clinical outcomes, improving public health. Significant advances in biosensor …