Drug repurposing holds the potential to bring medications with known safety profiles to new
patient populations. Numerous examples exist for the identification of new indications for …

In recent decades, in silico absorption, distribution, metabolism, excretion (ADME), and
toxicity (T) modelling as a tool for rational drug design has received considerable attention …

Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is a premier
public resource for literature-based, manually curated associations between chemicals …

Abstract For 20 years, the Comparative Toxicogenomics Database (CTD; https://ctdbase.
org) has provided high-quality, literature-based curated content describing how …

Ten years ago, the Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) was
developed out of a need to formalize, harmonize and centralize the information on …

Background The acquisition of resistance to chemotherapy is a major hurdle in the
successful application of cancer therapy. Several anticancer approaches, including …

Abstract Motivation Knowledge graphs (KGs) are being adopted in industry, commerce and
academia. Biomedical KG presents a challenge due to the complexity, size and …

Background: Drug repositioning is a new research area in drug development. It aims to
discover novel therapeutic uses of existing drugs. It could accelerate the process of …

Abstract The Comparative Toxicogenomics Database (CTD) is a curated database that
promotes understanding about the effects of environmental chemicals on human health …

Abstract The Comparative Toxicogenomics Database (CTD) is a public resource that
promotes understanding about the interaction of environmental chemicals with gene …