Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Antimicrobial resistance is a global public health threat, and the World Health Organization
(WHO) has announced a priority list of the most threatening pathogens against which novel …

Metabolic networks are interconnected and influence diverse cellular processes. The protein-
metabolite interactions that mediate these networks are frequently low affinity and …

Covering: 1995 to 2023Advances in bioanalytical methods, particularly mass spectrometry,
have provided valuable molecular insights into the mechanisms of life. Non-targeted …

Introduction In light of the ever-escalating problem of antimicrobial resistance, there is an
urgent need for the development of new antimicrobials. In this review, the role of …

Temperature‐sensitive (TS) mutants are a unique tool to perturb and engineer cellular
systems. Here, we constructed a CRISPR library with 15,120 Escherichia coli mutants, each …

Astaxanthin, a ketone carotenoid known for its high antioxidant activity, holds significant
potential for application in nutraceuticals, aquaculture, and cosmetics. The increasing …

In mass spectrometry (MS)‐based bottom‐up proteomics, protease digestion plays an
essential role in profiling both proteome sequences and post‐translational modifications …

The cell envelope of Gram-negative bacteria belonging to the Burkholderia cepacia complex
(Bcc) presents unique restrictions to antibiotic penetration. As a consequence, Bcc species …

Cannabis is widely used for medicinal and recreational purposes. As a result, there is
increased interest in its chemical components and their physiological effects. However …