In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …

Endothelial-to-mesenchymal transition is a dynamic process in which endothelial cells
suppress constituent endothelial properties and take on mesenchymal cell behaviors. To …

Diabetic cardiomyopathy (DCM) is one of the leading causes of heart failure in patients with
diabetes mellitus, with limited effective treatments. The cardioprotective effects of sodium …

Fibrotic diseases are characterized by net accumulation of extracellular matrix proteins in
affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been …

Endothelial cells and mesenchymal cells are two different cell types with distinct
morphologies, phenotypes, functions, and gene profiles. Accumulating evidence, notably …

Abstract Endothelial–mesenchymal transition (EndoMT), a cellular differentiation process in
which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells …

The tumor microenvironment (TME) consists of various components including cancer cells,
tumor vessels, cancer‐associated fibroblasts (CAFs), and inflammatory cells. These …

Endothelial-to-mesenchymal transition (EndMT) is closely related to the pathogenesis of
various diseases, including cardiac fibrosis. Transforming growth factor (TGF)-β1 strongly …